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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIAM2
All Species:
13.64
Human Site:
S1438
Identified Species:
42.86
UniProt:
Q8IVF5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVF5
NP_001010927.1
1701
190113
S1438
T
I
F
Q
L
C
C
S
D
S
E
S
K
T
N
Chimpanzee
Pan troglodytes
XP_527545
1701
190152
S1438
T
I
F
Q
L
C
C
S
D
S
E
S
K
T
N
Rhesus Macaque
Macaca mulatta
XP_001098107
1591
177452
S1347
L
Q
V
R
A
L
A
S
T
D
A
D
A
N
A
Dog
Lupus familis
XP_541162
1487
166908
V1242
N
E
S
K
T
N
I
V
K
V
I
R
S
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPF3
1715
192548
S1459
T
I
F
Q
L
C
C
S
D
S
E
N
K
T
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419687
1705
192295
S1441
T
I
F
Q
L
C
S
S
D
C
E
N
K
T
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91620
2061
229913
N1764
E
K
V
Y
V
L
S
N
S
T
A
D
F
R
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788791
1150
129570
H906
K
V
F
Q
F
S
S
H
S
S
D
L
R
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
38.9
78.3
N.A.
83.7
N.A.
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
24.6
Protein Similarity:
100
99.4
56.5
81.5
N.A.
89.1
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
41.8
N.A.
N.A.
39.8
P-Site Identity:
100
100
6.6
0
N.A.
86.6
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
13.3
6.6
N.A.
100
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
13
0
0
0
25
0
13
0
13
% A
% Cys:
0
0
0
0
0
50
38
0
0
13
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
13
13
25
0
0
0
% D
% Glu:
13
13
0
0
0
0
0
0
0
0
50
0
0
0
0
% E
% Phe:
0
0
63
0
13
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
13
0
0
0
13
0
0
13
0
% I
% Lys:
13
13
0
13
0
0
0
0
13
0
0
0
50
0
0
% K
% Leu:
13
0
0
0
50
25
0
0
0
0
0
13
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
13
0
13
0
0
0
25
0
25
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
0
63
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
13
13
13
0
% R
% Ser:
0
0
13
0
0
13
38
63
25
50
0
25
13
0
25
% S
% Thr:
50
0
0
0
13
0
0
0
13
13
0
0
0
50
0
% T
% Val:
0
13
25
0
13
0
0
13
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _