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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMAA All Species: 31.52
Human Site: S189 Identified Species: 77.04
UniProt: Q8IVH4 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVH4 NP_758454.1 418 46538 S189 S S C T S G G S L L G D K T R
Chimpanzee Pan troglodytes XP_526697 418 46408 S189 S S C T S G G S L L G D K T R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539752 882 96982 S652 S S C T S G G S L L G D K T R
Cat Felis silvestris
Mouse Mus musculus Q8C7H1 415 45914 S186 S S C T S G G S L L G D K T R
Rat Rattus norvegicus NP_001099644 415 46311 S186 S S C T S G G S L L G D K T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511017 505 56098 S276 S S C T S G G S L L G D K T R
Chicken Gallus gallus XP_420429 412 45903 S183 S S S T S G G S L L G D K T R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001098582 403 44225 S174 S S C T T G G S L M G D K T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22111 399 44198 R191 R N P K A Y I R Q S P T S G S
Sea Urchin Strong. purpuratus XP_796447 354 39431 N158 G G V T R N T N D T I L L C E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 N.A. 43.9 N.A. 80.3 79.1 N.A. 69.5 74.6 N.A. 64.8 N.A. N.A. N.A. 45.9 47.6
Protein Similarity: 100 99.2 N.A. 45.9 N.A. 87.8 87 N.A. 76.4 85.6 N.A. 78.2 N.A. N.A. N.A. 62.9 66.5
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 93.3 N.A. 86.6 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 93.3 N.A. 100 N.A. N.A. N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 70 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 80 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 80 80 0 0 0 80 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 80 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 80 70 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 80 % R
% Ser: 80 80 10 0 70 0 0 80 0 10 0 0 10 0 10 % S
% Thr: 0 0 0 90 10 0 10 0 0 10 0 10 0 80 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _