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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC41A1 All Species: 16.36
Human Site: S406 Identified Species: 32.73
UniProt: Q8IVJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVJ1 NP_776253.3 513 54901 S406 F F S P D V N S R S A R V L F
Chimpanzee Pan troglodytes XP_525038 363 39244 L264 R S A R V L F L L V V P G H L
Rhesus Macaque Macaca mulatta XP_001091355 477 50888 L378 R S A R V L F L L V V P G H L
Dog Lupus familis XP_536105 514 54966 S407 F F S P D V N S R S A R V L F
Cat Felis silvestris
Mouse Mus musculus Q8BJA2 512 54909 S405 F F S P D V N S R S A R V L F
Rat Rattus norvegicus Q3SWT5 462 50508 F363 V V P G H L I F F Y L I C L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518994 359 37584 A260 D N V A T P I A A S L G D L I
Chicken Gallus gallus Q5ZHX6 573 62388 K467 Y G T G V N N K S A Q V L L L
Frog Xenopus laevis Q6DFC0 561 60519 K455 C G T G V N N K S A Q V L L S
Zebra Danio Brachydanio rerio XP_682785 531 57188 S424 F F G S G V N S R S A K V L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624046 517 57156 R411 C A K G G H A R T A R V L L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789072 565 61116 S458 F F G K D M H S R S A R V L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.7 92.9 98 N.A. 97.6 48.1 N.A. 61 55.6 56.1 74.5 N.A. N.A. 51.2 N.A. 52.5
Protein Similarity: 100 70.7 92.9 98.6 N.A. 98.2 63.5 N.A. 64.1 69.8 70.2 82.6 N.A. N.A. 67.8 N.A. 65.8
P-Site Identity: 100 0 0 100 N.A. 100 6.6 N.A. 13.3 13.3 13.3 73.3 N.A. N.A. 6.6 N.A. 66.6
P-Site Similarity: 100 13.3 13.3 100 N.A. 100 13.3 N.A. 20 40 33.3 80 N.A. N.A. 20 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 9 0 0 9 9 9 25 42 0 0 0 0 % A
% Cys: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 34 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 42 42 0 0 0 0 17 9 9 0 0 0 0 0 34 % F
% Gly: 0 17 17 34 17 0 0 0 0 0 0 9 17 0 0 % G
% His: 0 0 0 0 9 9 9 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 17 0 0 0 0 9 0 0 17 % I
% Lys: 0 0 9 9 0 0 0 17 0 0 0 9 0 0 0 % K
% Leu: 0 0 0 0 0 25 0 17 17 0 17 0 25 84 25 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 17 50 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 25 0 9 0 0 0 0 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % Q
% Arg: 17 0 0 17 0 0 0 9 42 0 9 34 0 0 0 % R
% Ser: 0 17 25 9 0 0 0 42 17 50 0 0 0 0 9 % S
% Thr: 0 0 17 0 9 0 0 0 9 0 0 0 0 0 9 % T
% Val: 9 9 9 0 34 34 0 0 0 17 17 25 42 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _