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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC41A1 All Species: 17.88
Human Site: Y278 Identified Species: 35.76
UniProt: Q8IVJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVJ1 NP_776253.3 513 54901 Y278 S G I S W G L Y L E L N H W R
Chimpanzee Pan troglodytes XP_525038 363 39244 A143 Y I Y P L V C A F F V A L L P
Rhesus Macaque Macaca mulatta XP_001091355 477 50888 A257 Y I Y P L V C A F F V A L L P
Dog Lupus familis XP_536105 514 54966 Y279 S G I S W G L Y L E R D D W Q
Cat Felis silvestris
Mouse Mus musculus Q8BJA2 512 54909 Y277 S G I S W G L Y L E L K H W R
Rat Rattus norvegicus Q3SWT5 462 50508 W242 F L A L T P L W I F I A K Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518994 359 37584 I139 K D V T E V F I L V P A L L G
Chicken Gallus gallus Q5ZHX6 573 62388 Y339 A W I S Q G L Y T C L E T Y Y
Frog Xenopus laevis Q6DFC0 561 60519 Y327 A W I S Q G L Y N C L G S Y A
Zebra Danio Brachydanio rerio XP_682785 531 57188 Y296 A G I S T G L Y K E L E F N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624046 517 57156 Y285 S G I A S L L Y R A S E Y A P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789072 565 61116 F332 A W I S N L L F K N M G K Q H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.7 92.9 98 N.A. 97.6 48.1 N.A. 61 55.6 56.1 74.5 N.A. N.A. 51.2 N.A. 52.5
Protein Similarity: 100 70.7 92.9 98.6 N.A. 98.2 63.5 N.A. 64.1 69.8 70.2 82.6 N.A. N.A. 67.8 N.A. 65.8
P-Site Identity: 100 0 0 73.3 N.A. 93.3 6.6 N.A. 6.6 40 40 53.3 N.A. N.A. 33.3 N.A. 20
P-Site Similarity: 100 6.6 6.6 86.6 N.A. 93.3 26.6 N.A. 20 53.3 53.3 60 N.A. N.A. 46.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 9 9 0 0 0 17 0 9 0 34 0 9 9 % A
% Cys: 0 0 0 0 0 0 17 0 0 17 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 9 9 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 34 0 25 0 0 0 % E
% Phe: 9 0 0 0 0 0 9 9 17 25 0 0 9 0 0 % F
% Gly: 0 42 0 0 0 50 0 0 0 0 0 17 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 9 % H
% Ile: 0 17 67 0 0 0 0 9 9 0 9 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 17 0 0 9 17 0 0 % K
% Leu: 0 9 0 9 17 17 75 0 34 0 42 0 25 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 9 9 0 9 0 9 17 % N
% Pro: 0 0 0 17 0 9 0 0 0 0 9 0 0 0 25 % P
% Gln: 0 0 0 0 17 0 0 0 0 0 0 0 0 17 9 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 17 % R
% Ser: 34 0 0 59 9 0 0 0 0 0 9 0 9 0 0 % S
% Thr: 0 0 0 9 17 0 0 0 9 0 0 0 9 0 0 % T
% Val: 0 0 9 0 0 25 0 0 0 9 17 0 0 0 0 % V
% Trp: 0 25 0 0 25 0 0 9 0 0 0 0 0 25 0 % W
% Tyr: 17 0 17 0 0 0 0 59 0 0 0 0 9 17 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _