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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LEPREL1 All Species: 26.97
Human Site: S299 Identified Species: 74.17
UniProt: Q8IVL5 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVL5 NP_001127890.1 708 80984 S299 A T R P G R L S P I E N F L P
Chimpanzee Pan troglodytes XP_001160886 709 81109 S300 A T R P G R L S P I E N F L P
Rhesus Macaque Macaca mulatta XP_001092797 705 80645 S296 A T R P G R L S P I E N F L P
Dog Lupus familis XP_535843 709 80920 S300 A T R P G R L S P I E N F L P
Cat Felis silvestris
Mouse Mus musculus Q8CG71 703 80136 S294 A T R P G R L S P I E N F L P
Rat Rattus norvegicus Q4KLM6 703 79814 S294 A T R P G R L S P I E N F L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512529 532 60784 L158 E C A K S Y L L F H P D D E D
Chicken Gallus gallus Q6JHU7 694 78411 S285 A T R S G R I S P I E N F L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695073 721 83000 A312 H E C V R D L A T R P G R L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.8 92.2 N.A. 89.4 89.6 N.A. 62 72.5 N.A. 55.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.4 94.5 N.A. 93.3 92.9 N.A. 68.3 82.9 N.A. 71.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 93.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 78 0 12 0 0 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 0 0 0 12 12 0 12 % D
% Glu: 12 12 0 0 0 0 0 0 0 0 78 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 78 0 0 % F
% Gly: 0 0 0 0 78 0 0 0 0 0 0 12 0 0 0 % G
% His: 12 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 78 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 89 12 0 0 0 0 0 89 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 % N
% Pro: 0 0 0 67 0 0 0 0 78 0 23 0 0 0 78 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 78 0 12 78 0 0 0 12 0 0 12 0 0 % R
% Ser: 0 0 0 12 12 0 0 78 0 0 0 0 0 0 12 % S
% Thr: 0 78 0 0 0 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _