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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LEPREL2 All Species: 8.48
Human Site: S19 Identified Species: 23.33
UniProt: Q8IVL6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVL6 NP_055077.2 736 81837 S19 L L L P P P G S P E P P G L T
Chimpanzee Pan troglodytes XP_001160886 709 81109 L17 L L L L L P L L L L P P P L W
Rhesus Macaque Macaca mulatta XP_001110287 736 81914 S19 L L L P P P G S P E P P G L A
Dog Lupus familis XP_853513 744 82725 S19 L L L P P P G S P E P P G L A
Cat Felis silvestris
Mouse Mus musculus Q8CG70 732 81682 P21 P P P G S P E P P E P P G L A
Rat Rattus norvegicus Q9R1J8 728 82371 A9 V A V A A A A A S R A T A E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6JHU8 725 81657 L10 L L L P L L P L L V W A A G P
Frog Xenopus laevis NP_001084503 765 87510 G9 A L S L L F T G T F F F L L S
Zebra Danio Brachydanio rerio XP_696266 731 82504 I23 F I I N Y I C I T A G S G L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.3 97.4 87.2 N.A. 86.9 43.4 N.A. N.A. 43.8 40.3 41.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.2 98.6 90.9 N.A. 92.5 60.1 N.A. N.A. 59.9 58 57.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 93.3 93.3 N.A. 46.6 0 N.A. N.A. 26.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 93.3 93.3 N.A. 46.6 26.6 N.A. N.A. 26.6 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 12 12 12 12 12 0 12 12 12 23 0 34 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 12 0 0 45 0 0 0 12 0 % E
% Phe: 12 0 0 0 0 12 0 0 0 12 12 12 0 0 0 % F
% Gly: 0 0 0 12 0 0 34 12 0 0 12 0 56 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 12 0 0 12 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 56 67 56 23 34 12 12 23 23 12 0 0 12 78 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 12 12 45 34 56 12 12 45 0 56 56 12 0 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % R
% Ser: 0 0 12 0 12 0 0 34 12 0 0 12 0 0 34 % S
% Thr: 0 0 0 0 0 0 12 0 23 0 0 12 0 0 12 % T
% Val: 12 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 12 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _