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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEPREL2
All Species:
12.12
Human Site:
S252
Identified Species:
33.33
UniProt:
Q8IVL6
Number Species:
8
Phosphosite Substitution
Charge Score:
0.63
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVL6
NP_055077.2
736
81837
S252
G
S
L
A
Q
M
E
S
C
R
A
D
C
E
G
Chimpanzee
Pan troglodytes
XP_001160886
709
81109
E247
E
Y
F
I
E
D
I
E
C
R
T
L
C
E
G
Rhesus Macaque
Macaca mulatta
XP_001110287
736
81914
S252
G
S
L
A
Q
M
E
S
C
R
A
D
C
Q
G
Dog
Lupus familis
XP_853513
744
82725
S259
E
I
L
A
Q
M
E
S
C
R
A
G
C
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG70
732
81682
S250
G
S
L
A
H
M
E
S
C
R
A
A
C
E
G
Rat
Rattus norvegicus
Q9R1J8
728
82371
E233
E
Y
F
V
A
D
E
E
C
R
A
L
C
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6JHU8
725
81657
E234
E
Y
F
V
A
D
T
E
C
R
A
L
C
E
G
Frog
Xenopus laevis
NP_001084503
765
87510
E230
E
Y
F
V
A
D
L
E
C
R
S
M
C
E
G
Zebra Danio
Brachydanio rerio
XP_696266
731
82504
E246
E
T
L
K
Q
T
E
E
C
R
A
Q
C
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.3
97.4
87.2
N.A.
86.9
43.4
N.A.
N.A.
43.8
40.3
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.2
98.6
90.9
N.A.
92.5
60.1
N.A.
N.A.
59.9
58
57.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
93.3
80
N.A.
86.6
46.6
N.A.
N.A.
40
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
80
N.A.
86.6
46.6
N.A.
N.A.
40
40
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
34
0
0
0
0
0
78
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
100
0
0
0
100
0
0
% C
% Asp:
0
0
0
0
0
45
0
0
0
0
0
23
0
0
0
% D
% Glu:
67
0
0
0
12
0
67
56
0
0
0
0
0
78
0
% E
% Phe:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
0
0
0
0
0
0
0
0
12
0
0
89
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
12
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
56
0
0
0
12
0
0
0
0
34
0
0
0
% L
% Met:
0
0
0
0
0
45
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
45
0
0
0
0
0
0
12
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
34
0
0
0
0
0
45
0
0
12
0
0
0
0
% S
% Thr:
0
12
0
0
0
12
12
0
0
0
12
0
0
0
12
% T
% Val:
0
0
0
34
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _