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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPO All Species: 13.03
Human Site: S220 Identified Species: 26.06
UniProt: Q8IVL8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVL8 NP_775100.1 374 42529 S220 P E T K A V A S F I E S K K D
Chimpanzee Pan troglodytes XP_001138601 374 42618 S220 P E T K A I A S F I E S K K D
Rhesus Macaque Macaca mulatta XP_001098839 437 50916 T216 F V K E A L L T H K S D P A M
Dog Lupus familis XP_852108 425 48925 S271 P E T K A V S S F V E S K K E
Cat Felis silvestris
Mouse Mus musculus Q9JHH6 422 48852 A268 K H W C E K G A S S S S C S E
Rat Rattus norvegicus P19223 415 47497 R263 W C E V G A S R S P C S E T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511380 437 50943 P287 D E G A S L Y P C D D T Y C G
Chicken Gallus gallus XP_421950 415 47690 S266 S W G T L G V S Y N C S S E I
Frog Xenopus laevis NP_001087305 356 40950 K202 P E A N A V S K L L G S L K S
Zebra Danio Brachydanio rerio XP_002660496 363 40957 D208 P E A E A V T D F L G A H Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL86 430 47642 Y279 S S A C S D T Y A G P S A F S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38836 430 49811 S273 K A H T H A C S E E Y S G E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 37.9 72 N.A. 39.5 38.7 N.A. 38.4 54.7 57.7 48.1 N.A. 31.6 N.A. N.A. N.A.
Protein Similarity: 100 99.1 54.6 80 N.A. 56.6 56.1 N.A. 54.2 65.5 73.5 66.5 N.A. 51.1 N.A. N.A. N.A.
P-Site Identity: 100 93.3 6.6 80 N.A. 6.6 6.6 N.A. 6.6 13.3 40 33.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 20 20 N.A. 33.3 26.6 53.3 66.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 25 9 50 17 17 9 9 0 0 9 9 9 0 % A
% Cys: 0 9 0 17 0 0 9 0 9 0 17 0 9 9 0 % C
% Asp: 9 0 0 0 0 9 0 9 0 9 9 9 0 0 17 % D
% Glu: 0 50 9 17 9 0 0 0 9 9 25 0 9 17 17 % E
% Phe: 9 0 0 0 0 0 0 0 34 0 0 0 0 9 0 % F
% Gly: 0 0 17 0 9 9 9 0 0 9 17 0 9 0 9 % G
% His: 0 9 9 0 9 0 0 0 9 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 9 % I
% Lys: 17 0 9 25 0 9 0 9 0 9 0 0 25 34 0 % K
% Leu: 0 0 0 0 9 17 9 0 9 17 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 9 % N
% Pro: 42 0 0 0 0 0 0 9 0 9 9 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 17 9 0 0 17 0 25 42 17 9 17 75 9 9 17 % S
% Thr: 0 0 25 17 0 0 17 9 0 0 0 9 0 9 9 % T
% Val: 0 9 0 9 0 34 9 0 0 9 0 0 0 0 0 % V
% Trp: 9 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 9 9 0 9 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _