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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC21 All Species: 24.55
Human Site: T232 Identified Species: 45
UniProt: Q8IVQ6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVQ6 NP_848661.1 265 31385 T232 P R K P W Q Q T F S E V F G T
Chimpanzee Pan troglodytes XP_001146243 328 37429 K268 T G S W Q S V K E T F G G D F
Rhesus Macaque Macaca mulatta XP_001105377 226 26796 T193 P R K P W Q Q T F S E V F G T
Dog Lupus familis XP_538667 459 52945 T426 P R K P W Q Q T F S E V F G T
Cat Felis silvestris
Mouse Mus musculus Q9D270 265 31313 T232 P R K P W Q Q T F S E V F G T
Rat Rattus norvegicus Q923G5 308 35213 K259 I E R L K S E K P T W E R R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507467 265 31169 T232 P R K P W Q Q T F S E V F G T
Chicken Gallus gallus NP_001026609 265 31324 T232 P R K P W Q Q T F S E V F G T
Frog Xenopus laevis Q5FWL7 338 39422 S303 P M R M A C E S R N P L L A A
Zebra Danio Brachydanio rerio NP_001116527 263 30926 A232 R P W Q Q A M A E V F G T R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611070 293 33362 Q263 K S R L K S I Q S V F G R F S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12006 378 44470 Q219 F N S G R L T Q K L I D N T W
Red Bread Mold Neurospora crassa Q7RWM9 429 49597 M324 G G V Y K R R M A A D G S R E
Conservation
Percent
Protein Identity: 100 28.6 84.1 56.4 N.A. 97.7 28.2 N.A. 89.4 82.6 25.7 64.1 N.A. 28.3 N.A. N.A. N.A.
Protein Similarity: 100 42.3 84.9 57 N.A. 98.8 45.7 N.A. 95.4 91.3 36.3 78.1 N.A. 46.7 N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 100 100 6.6 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 20 N.A. 100 100 40 0 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.7 23
Protein Similarity: N.A. N.A. N.A. N.A. 35.7 34.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 0 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 8 8 8 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 0 % D
% Glu: 0 8 0 0 0 0 16 0 16 0 47 8 0 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 47 0 24 0 47 8 8 % F
% Gly: 8 16 0 8 0 0 0 0 0 0 0 31 8 47 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 47 0 24 0 0 16 8 0 0 0 0 0 0 % K
% Leu: 0 0 0 16 0 8 0 0 0 8 0 8 8 0 8 % L
% Met: 0 8 0 8 0 0 8 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 54 8 0 47 0 0 0 0 8 0 8 0 0 0 0 % P
% Gln: 0 0 0 8 16 47 47 16 0 0 0 0 0 0 0 % Q
% Arg: 8 47 24 0 8 8 8 0 8 0 0 0 16 24 0 % R
% Ser: 0 8 16 0 0 24 0 8 8 47 0 0 8 0 8 % S
% Thr: 8 0 0 0 0 0 8 47 0 16 0 0 8 8 47 % T
% Val: 0 0 8 0 0 0 8 0 0 16 0 47 0 0 0 % V
% Trp: 0 0 8 8 47 0 0 0 0 0 8 0 0 0 16 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _