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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC21
All Species:
24.85
Human Site:
Y159
Identified Species:
45.56
UniProt:
Q8IVQ6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVQ6
NP_848661.1
265
31385
Y159
F
S
F
C
H
Y
Y
Y
F
L
P
L
K
K
R
Chimpanzee
Pan troglodytes
XP_001146243
328
37429
H195
M
V
G
F
H
F
L
H
C
F
E
E
D
W
T
Rhesus Macaque
Macaca mulatta
XP_001105377
226
26796
Y120
F
S
F
C
H
Y
Y
Y
F
L
P
L
K
K
R
Dog
Lupus familis
XP_538667
459
52945
Y353
F
S
F
C
H
Y
Y
Y
F
L
P
V
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D270
265
31313
Y159
F
S
F
C
H
Y
Y
Y
F
L
P
L
K
K
R
Rat
Rattus norvegicus
Q923G5
308
35213
S199
L
C
G
L
Q
F
I
S
C
V
R
G
Q
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507467
265
31169
Y159
I
S
F
C
H
Y
Y
Y
L
L
P
L
K
R
R
Chicken
Gallus gallus
NP_001026609
265
31324
Y159
L
D
F
C
H
Y
Y
Y
F
L
P
L
K
K
D
Frog
Xenopus laevis
Q5FWL7
338
39422
W236
F
L
F
G
Y
H
C
W
L
V
S
L
N
R
T
Zebra Danio
Brachydanio rerio
NP_001116527
263
30926
Y159
L
D
F
C
Q
Y
Y
Y
F
L
P
L
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611070
293
33362
E190
L
V
L
T
Q
F
A
E
C
V
K
N
D
W
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12006
378
44470
I145
F
C
I
Q
A
K
R
I
Y
F
I
W
Q
Q
R
Red Bread Mold
Neurospora crassa
Q7RWM9
429
49597
G219
T
L
Y
G
G
V
L
G
L
V
I
I
R
A
K
Conservation
Percent
Protein Identity:
100
28.6
84.1
56.4
N.A.
97.7
28.2
N.A.
89.4
82.6
25.7
64.1
N.A.
28.3
N.A.
N.A.
N.A.
Protein Similarity:
100
42.3
84.9
57
N.A.
98.8
45.7
N.A.
95.4
91.3
36.3
78.1
N.A.
46.7
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
0
N.A.
80
80
20
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
86.6
80
53.3
60
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
23
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.7
34.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
16
0
54
0
0
8
0
24
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
0
0
0
0
0
0
0
16
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% E
% Phe:
47
0
62
8
0
24
0
0
47
16
0
0
0
0
0
% F
% Gly:
0
0
16
16
8
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
54
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
8
8
0
0
16
8
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
8
0
47
39
8
% K
% Leu:
31
16
8
8
0
0
16
0
24
54
0
54
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
0
8
24
0
0
0
0
0
0
0
16
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
8
0
8
16
54
% R
% Ser:
0
39
0
0
0
0
0
8
0
0
8
0
8
8
0
% S
% Thr:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
24
% T
% Val:
0
16
0
0
0
8
0
0
0
31
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
8
0
24
0
% W
% Tyr:
0
0
8
0
8
54
54
54
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _