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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC21 All Species: 23.03
Human Site: Y40 Identified Species: 42.22
UniProt: Q8IVQ6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVQ6 NP_848661.1 265 31385 Y40 K I V L F P H Y E E G H I P G
Chimpanzee Pan troglodytes XP_001146243 328 37429 S69 L F V M L I P S R D Y V Y S I
Rhesus Macaque Macaca mulatta XP_001105377 226 26796 G34 R A S I T D P G R L P E N P K
Dog Lupus familis XP_538667 459 52945 Y234 K I V L F P H Y E E G H I P G
Cat Felis silvestris
Mouse Mus musculus Q9D270 265 31313 Y40 K I V L F P H Y E E G H I P G
Rat Rattus norvegicus Q923G5 308 35213 S73 T F V M L L P S K D F W Y S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507467 265 31169 Y40 Q I V L Y P H Y E E G H I S A
Chicken Gallus gallus NP_001026609 265 31324 Y40 K V I L F P H Y E E G H I S A
Frog Xenopus laevis Q5FWL7 338 39422 V48 W E L C L V T V T N P A E K A
Zebra Danio Brachydanio rerio NP_001116527 263 30926 Y40 K L V L L P H Y A E G H I T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611070 293 33362 S64 M R L I L L P S N Y T V F S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12006 378 44470 Q40 N F L S V P K Q I T F E F C L
Red Bread Mold Neurospora crassa Q7RWM9 429 49597 G91 F F L L L S V G E Y L Y L P V
Conservation
Percent
Protein Identity: 100 28.6 84.1 56.4 N.A. 97.7 28.2 N.A. 89.4 82.6 25.7 64.1 N.A. 28.3 N.A. N.A. N.A.
Protein Similarity: 100 42.3 84.9 57 N.A. 98.8 45.7 N.A. 95.4 91.3 36.3 78.1 N.A. 46.7 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 100 N.A. 100 6.6 N.A. 73.3 73.3 0 66.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 20 100 N.A. 100 26.6 N.A. 86.6 86.6 6.6 73.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.7 23
Protein Similarity: N.A. N.A. N.A. N.A. 35.7 34.7
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 8 0 0 8 0 0 31 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 16 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 47 47 0 16 8 0 0 % E
% Phe: 8 31 0 0 31 0 0 0 0 0 16 0 16 0 0 % F
% Gly: 0 0 0 0 0 0 0 16 0 0 47 0 0 0 24 % G
% His: 0 0 0 0 0 0 47 0 0 0 0 47 0 0 0 % H
% Ile: 0 31 8 16 0 8 0 0 8 0 0 0 47 0 8 % I
% Lys: 39 0 0 0 0 0 8 0 8 0 0 0 0 8 8 % K
% Leu: 8 8 31 54 47 16 0 0 0 8 8 0 8 0 8 % L
% Met: 8 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 8 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 54 31 0 0 0 16 0 0 39 0 % P
% Gln: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 16 0 0 0 0 0 0 % R
% Ser: 0 0 8 8 0 8 0 24 0 0 0 0 0 39 0 % S
% Thr: 8 0 0 0 8 0 8 0 8 8 8 0 0 8 8 % T
% Val: 0 8 54 0 8 8 8 8 0 0 0 16 0 0 16 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 47 0 16 8 8 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _