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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCAT
All Species:
10
Human Site:
S17
Identified Species:
20
UniProt:
Q8IVS2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVS2
NP_055322.1
390
42962
S17
W
V
R
G
L
G
A
S
Y
R
R
G
A
S
S
Chimpanzee
Pan troglodytes
XP_525618
390
42910
S17
W
V
R
G
L
G
A
S
Y
R
R
G
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001108205
390
42800
S17
W
A
R
G
L
G
A
S
G
R
R
G
V
S
S
Dog
Lupus familis
XP_851896
403
43861
G39
W
A
R
G
W
G
A
G
C
R
R
G
A
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3F5
381
41910
R17
W
A
W
R
S
W
G
R
R
A
A
S
S
L
R
Rat
Rattus norvegicus
XP_235527
380
41814
R17
W
A
W
G
S
W
G
R
R
P
A
S
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425506
361
39619
Frog
Xenopus laevis
NP_001088934
388
42859
Q17
C
L
C
G
P
L
R
Q
V
V
L
P
L
G
N
Zebra Danio
Brachydanio rerio
NP_001038508
364
40460
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T3L6
379
42067
W19
R
I
T
G
A
L
S
W
S
R
W
S
S
D
A
Honey Bee
Apis mellifera
XP_395747
414
46995
N21
G
P
K
Y
Y
W
L
N
R
I
N
Q
I
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797475
416
45479
S21
N
Q
F
S
I
S
S
S
H
R
D
T
T
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
94.3
76.9
N.A.
74
75.6
N.A.
N.A.
51.7
60.2
56.6
N.A.
41.7
35.9
N.A.
47.6
Protein Similarity:
100
99.4
96.1
83.3
N.A.
83.3
83.3
N.A.
N.A.
65.3
73.3
73.8
N.A.
59.2
57.7
N.A.
64.1
P-Site Identity:
100
100
80
66.6
N.A.
6.6
13.3
N.A.
N.A.
0
6.6
0
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
100
80
66.6
N.A.
13.3
20
N.A.
N.A.
0
20
0
N.A.
40
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
9
0
34
0
0
9
17
0
25
0
9
% A
% Cys:
9
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
59
0
34
17
9
9
0
0
34
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
0
0
9
0
0
9
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
25
17
9
0
0
0
9
0
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
17
% N
% Pro:
0
9
0
0
9
0
0
0
0
9
0
9
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
9
0
34
9
0
0
9
17
25
50
34
0
0
0
17
% R
% Ser:
0
0
0
9
17
9
17
34
9
0
0
25
25
50
25
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
9
9
0
0
% T
% Val:
0
17
0
0
0
0
0
0
9
9
0
0
9
0
0
% V
% Trp:
50
0
17
0
9
25
0
9
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _