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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCAT
All Species:
11.21
Human Site:
S322
Identified Species:
22.42
UniProt:
Q8IVS2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVS2
NP_055322.1
390
42962
S322
L
L
A
Q
Q
L
V
S
P
V
K
W
E
Q
T
Chimpanzee
Pan troglodytes
XP_525618
390
42910
S322
L
L
A
Q
Q
L
V
S
P
V
K
W
E
Q
T
Rhesus Macaque
Macaca mulatta
XP_001108205
390
42800
S322
L
L
A
Q
Q
V
V
S
P
V
K
W
E
Q
T
Dog
Lupus familis
XP_851896
403
43861
Q340
I
Q
K
L
L
V
Q
Q
V
V
S
P
V
K
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3F5
381
41910
V319
K
L
L
G
Q
Q
V
V
S
P
V
K
W
E
Q
Rat
Rattus norvegicus
XP_235527
380
41814
V318
K
L
L
G
Q
Q
V
V
S
P
V
K
W
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425506
361
39619
V299
K
L
L
V
K
Q
L
V
S
P
V
L
W
E
Q
Frog
Xenopus laevis
NP_001088934
388
42859
V326
Q
L
L
A
K
Q
V
V
S
P
V
K
W
E
Q
Zebra Danio
Brachydanio rerio
NP_001038508
364
40460
A302
K
H
I
R
N
Q
L
A
K
Q
L
V
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T3L6
379
42067
K315
G
K
P
Y
R
H
A
K
H
I
L
T
Q
L
P
Honey Bee
Apis mellifera
XP_395747
414
46995
S322
L
M
E
P
A
L
K
S
V
S
E
M
L
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797475
416
45479
D344
I
C
I
H
S
N
V
D
G
K
P
Y
G
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
94.3
76.9
N.A.
74
75.6
N.A.
N.A.
51.7
60.2
56.6
N.A.
41.7
35.9
N.A.
47.6
Protein Similarity:
100
99.4
96.1
83.3
N.A.
83.3
83.3
N.A.
N.A.
65.3
73.3
73.8
N.A.
59.2
57.7
N.A.
64.1
P-Site Identity:
100
100
93.3
6.6
N.A.
20
20
N.A.
N.A.
6.6
13.3
0
N.A.
0
20
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
26.6
N.A.
N.A.
26.6
26.6
20
N.A.
20
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
9
9
0
9
9
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
9
0
25
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
17
0
0
0
0
9
0
0
0
9
0
0
% G
% His:
0
9
0
9
0
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
17
0
17
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
34
9
9
0
17
0
9
9
9
9
25
25
0
17
0
% K
% Leu:
34
59
34
9
9
25
17
0
0
0
17
9
9
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
0
0
0
0
25
34
9
9
0
9
17
% P
% Gln:
9
9
0
25
42
42
9
9
0
9
0
0
9
25
34
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
34
34
9
9
0
9
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
25
% T
% Val:
0
0
0
9
0
17
59
34
17
34
34
9
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
25
34
0
9
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _