KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCAT
All Species:
26.97
Human Site:
T117
Identified Species:
53.94
UniProt:
Q8IVS2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVS2
NP_055322.1
390
42962
T117
P
Q
E
T
L
D
R
T
V
H
C
Q
P
A
I
Chimpanzee
Pan troglodytes
XP_525618
390
42910
T117
P
Q
E
T
L
D
R
T
V
H
C
Q
P
A
I
Rhesus Macaque
Macaca mulatta
XP_001108205
390
42800
T117
P
Q
E
T
L
D
R
T
V
H
C
Q
P
A
I
Dog
Lupus familis
XP_851896
403
43861
T138
P
Q
E
A
L
D
R
T
A
H
C
Q
P
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3F5
381
41910
T115
P
Q
E
D
L
D
R
T
V
H
C
Q
P
A
V
Rat
Rattus norvegicus
XP_235527
380
41814
T114
P
Q
E
D
L
D
R
T
V
H
C
Q
P
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425506
361
39619
M100
R
Y
P
G
V
R
D
M
Y
R
L
A
E
K
P
Frog
Xenopus laevis
NP_001088934
388
42859
T122
P
Q
E
T
L
N
K
T
V
H
C
Q
P
A
I
Zebra Danio
Brachydanio rerio
NP_001038508
364
40460
V103
E
K
D
L
M
K
T
V
H
C
Q
P
A
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T3L6
379
42067
P115
L
K
I
C
L
E
G
P
R
E
K
L
N
R
T
Honey Bee
Apis mellifera
XP_395747
414
46995
K121
T
I
K
V
G
M
I
K
K
Y
L
R
Y
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797475
416
45479
Y141
V
A
S
E
I
L
G
Y
E
K
L
Q
L
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
94.3
76.9
N.A.
74
75.6
N.A.
N.A.
51.7
60.2
56.6
N.A.
41.7
35.9
N.A.
47.6
Protein Similarity:
100
99.4
96.1
83.3
N.A.
83.3
83.3
N.A.
N.A.
65.3
73.3
73.8
N.A.
59.2
57.7
N.A.
64.1
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
N.A.
0
86.6
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
6.6
100
20
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
0
9
0
0
9
9
59
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
9
59
0
0
9
0
% C
% Asp:
0
0
9
17
0
50
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
59
9
0
9
0
0
9
9
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
9
0
17
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
59
0
0
0
0
0
% H
% Ile:
0
9
9
0
9
0
9
0
0
0
0
0
0
0
34
% I
% Lys:
0
17
9
0
0
9
9
9
9
9
9
0
0
9
0
% K
% Leu:
9
0
0
9
67
9
0
0
0
0
25
9
9
0
9
% L
% Met:
0
0
0
0
9
9
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
59
0
9
0
0
0
0
9
0
0
0
9
59
0
9
% P
% Gln:
0
59
0
0
0
0
0
0
0
0
9
67
0
0
0
% Q
% Arg:
9
0
0
0
0
9
50
0
9
9
0
9
0
9
0
% R
% Ser:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% S
% Thr:
9
0
0
34
0
0
9
59
0
0
0
0
0
0
9
% T
% Val:
9
0
0
9
9
0
0
9
50
0
0
0
0
9
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
9
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _