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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCAT All Species: 10.61
Human Site: T345 Identified Species: 21.21
UniProt: Q8IVS2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVS2 NP_055322.1 390 42962 T345 K G R G F P Q T F E V G P G R
Chimpanzee Pan troglodytes XP_525618 390 42910 T345 K G R G F P Q T F E V G P G R
Rhesus Macaque Macaca mulatta XP_001108205 390 42800 T345 K G R E F P Q T F E V G P G R
Dog Lupus familis XP_851896 403 43861 F363 E R K K G V E F P K T F E V G
Cat Felis silvestris
Mouse Mus musculus Q8R3F5 381 41910 S342 K K G M E F P S T Y E V G P G
Rat Rattus norvegicus XP_235527 380 41814 S341 K K G M E F P S T F E V G P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425506 361 39619 Y322 K Q G M E F P Y T Y E V G P G
Frog Xenopus laevis NP_001088934 388 42859 Y349 K S G T D F P Y T Y E V G P G
Zebra Danio Brachydanio rerio NP_001038508 364 40460 Q325 I Y Q R A Q G Q E F P H T Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T3L6 379 42067 M338 W E Q T L H E M Y E R K Q G V
Honey Bee Apis mellifera XP_395747 414 46995 G345 K V Y S N Y K G Y P Y S N L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797475 416 45479 L367 K Q V V E P V L W E Q T M H C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94.3 76.9 N.A. 74 75.6 N.A. N.A. 51.7 60.2 56.6 N.A. 41.7 35.9 N.A. 47.6
Protein Similarity: 100 99.4 96.1 83.3 N.A. 83.3 83.3 N.A. N.A. 65.3 73.3 73.8 N.A. 59.2 57.7 N.A. 64.1
P-Site Identity: 100 100 93.3 0 N.A. 6.6 6.6 N.A. N.A. 6.6 6.6 0 N.A. 13.3 13.3 N.A. 20
P-Site Similarity: 100 100 93.3 26.6 N.A. 13.3 13.3 N.A. N.A. 6.6 6.6 6.6 N.A. 33.3 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 9 34 0 17 0 9 42 34 0 9 0 9 % E
% Phe: 0 0 0 0 25 34 0 9 25 17 0 9 0 0 0 % F
% Gly: 0 25 34 17 9 0 9 9 0 0 0 25 34 34 42 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 9 0 9 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 75 17 9 9 0 0 9 0 0 9 0 9 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 9 0 0 0 0 0 9 0 % L
% Met: 0 0 0 25 0 0 0 9 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 34 34 0 9 9 9 0 25 34 0 % P
% Gln: 0 17 17 0 0 9 25 9 0 0 9 0 9 0 0 % Q
% Arg: 0 9 25 9 0 0 0 0 0 0 9 0 0 0 34 % R
% Ser: 0 9 0 9 0 0 0 17 0 0 0 9 0 0 0 % S
% Thr: 0 0 0 17 0 0 0 25 34 0 9 9 9 0 0 % T
% Val: 0 9 9 9 0 9 9 0 0 0 25 34 0 9 9 % V
% Trp: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 0 9 0 17 17 25 9 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _