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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCAT
All Species:
13.33
Human Site:
Y298
Identified Species:
26.67
UniProt:
Q8IVS2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVS2
NP_055322.1
390
42962
Y298
K
K
P
L
V
S
V
Y
S
N
V
H
A
H
R
Chimpanzee
Pan troglodytes
XP_525618
390
42910
Y298
K
K
P
L
V
S
V
Y
S
N
V
H
G
H
R
Rhesus Macaque
Macaca mulatta
XP_001108205
390
42800
Y298
K
K
P
L
V
S
V
Y
S
N
V
H
G
H
R
Dog
Lupus familis
XP_851896
403
43861
L315
S
V
G
V
K
K
P
L
V
S
V
H
S
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3F5
381
41910
H296
K
K
P
L
V
A
V
H
S
N
V
S
G
Q
K
Rat
Rattus norvegicus
XP_235527
380
41814
H295
K
K
P
L
V
A
V
H
S
N
V
S
G
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425506
361
39619
Y276
Q
K
P
L
I
C
V
Y
S
N
V
D
S
K
K
Frog
Xenopus laevis
NP_001088934
388
42859
F303
K
Q
P
L
V
P
V
F
C
N
V
D
G
K
R
Zebra Danio
Brachydanio rerio
NP_001038508
364
40460
E279
K
I
E
V
R
R
P
E
I
S
V
H
S
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T3L6
379
42067
T292
P
F
T
K
A
L
K
T
V
R
L
Q
D
P
V
Honey Bee
Apis mellifera
XP_395747
414
46995
F297
I
E
K
N
K
T
E
F
N
L
E
N
V
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797475
416
45479
S318
F
H
T
S
L
M
S
S
A
Q
Q
P
I
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
94.3
76.9
N.A.
74
75.6
N.A.
N.A.
51.7
60.2
56.6
N.A.
41.7
35.9
N.A.
47.6
Protein Similarity:
100
99.4
96.1
83.3
N.A.
83.3
83.3
N.A.
N.A.
65.3
73.3
73.8
N.A.
59.2
57.7
N.A.
64.1
P-Site Identity:
100
93.3
93.3
13.3
N.A.
60
66.6
N.A.
N.A.
53.3
53.3
20
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
93.3
93.3
40
N.A.
80
86.6
N.A.
N.A.
80
66.6
46.6
N.A.
6.6
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
17
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% D
% Glu:
0
9
9
0
0
0
9
9
0
0
9
0
0
0
0
% E
% Phe:
9
9
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
42
0
0
% G
% His:
0
9
0
0
0
0
0
17
0
0
0
42
0
34
0
% H
% Ile:
9
9
0
0
9
0
0
0
9
0
0
0
9
0
0
% I
% Lys:
59
50
9
9
17
9
9
0
0
0
0
0
0
17
34
% K
% Leu:
0
0
0
59
9
9
0
9
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
59
0
9
0
17
0
% N
% Pro:
9
0
59
0
0
9
17
0
0
0
0
9
0
9
0
% P
% Gln:
9
9
0
0
0
0
0
0
0
9
9
9
0
9
0
% Q
% Arg:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
42
% R
% Ser:
9
0
0
9
0
25
9
9
50
17
0
17
25
17
0
% S
% Thr:
0
0
17
0
0
9
0
9
0
0
0
0
0
0
0
% T
% Val:
0
9
0
17
50
0
59
0
17
0
75
0
9
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _