KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLYCTK
All Species:
19.7
Human Site:
Y274
Identified Species:
39.39
UniProt:
Q8IVS8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVS8
NP_001138423.1
523
55253
Y274
C
L
H
I
L
N
R
Y
G
L
R
A
A
L
P
Chimpanzee
Pan troglodytes
XP_001171685
523
55257
Y274
C
L
H
I
L
N
R
Y
G
L
R
A
A
L
P
Rhesus Macaque
Macaca mulatta
XP_001086096
460
48772
V237
A
A
Y
P
A
Q
V
V
S
L
I
L
S
D
V
Dog
Lupus familis
XP_541854
523
54931
Y274
C
L
H
I
L
N
H
Y
G
L
R
A
A
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZY2
523
55274
Y274
C
L
H
I
L
N
H
Y
G
L
R
A
A
L
P
Rat
Rattus norvegicus
Q0VGK3
523
55169
Y274
C
L
H
I
L
N
H
Y
G
L
R
A
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515750
474
50086
H223
C
L
H
I
L
T
Q
H
G
L
R
A
A
L
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08BL7
502
52590
Y242
V
W
A
I
L
D
N
Y
K
L
S
D
S
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQC4
487
52774
H247
P
S
D
I
L
K
K
H
H
V
W
E
E
L
S
Honey Bee
Apis mellifera
XP_395012
499
55437
C233
E
A
S
S
L
E
A
C
N
Y
K
L
T
P
I
Nematode Worm
Caenorhab. elegans
Q09235
458
49762
E236
F
I
I
S
N
I
L
E
S
L
K
I
N
K
L
Sea Urchin
Strong. purpuratus
XP_790018
517
54304
F259
C
L
K
I
F
Q
E
F
A
I
S
K
G
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
85.2
87.9
N.A.
84.5
83.5
N.A.
65.1
N.A.
N.A.
51.6
N.A.
36.1
26.3
31.7
44.1
Protein Similarity:
100
99.6
86.6
91.9
N.A.
90.2
89.8
N.A.
73.8
N.A.
N.A.
65.7
N.A.
53.3
42.2
49.7
62.1
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
N.A.
40
N.A.
20
6.6
6.6
20
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
53.3
N.A.
40
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
0
9
0
9
0
9
0
0
50
50
0
0
% A
% Cys:
59
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
0
0
9
0
17
0
% D
% Glu:
9
0
0
0
0
9
9
9
0
0
0
9
9
0
0
% E
% Phe:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
50
0
0
0
9
0
0
% G
% His:
0
0
50
0
0
0
25
17
9
0
0
0
0
0
0
% H
% Ile:
0
9
9
75
0
9
0
0
0
9
9
9
0
0
17
% I
% Lys:
0
0
9
0
0
9
9
0
9
0
17
9
0
9
0
% K
% Leu:
0
59
0
0
75
0
9
0
0
75
0
17
0
67
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
42
9
0
9
0
0
0
9
0
0
% N
% Pro:
9
0
0
9
0
0
0
0
0
0
0
0
0
9
59
% P
% Gln:
0
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
0
0
0
50
0
0
0
0
% R
% Ser:
0
9
9
17
0
0
0
0
17
0
17
0
17
0
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
0
9
9
0
9
0
0
0
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
50
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _