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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HERC6
All Species:
8.18
Human Site:
S216
Identified Species:
22.5
UniProt:
Q8IVU3
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVU3
NP_060382.3
1022
115126
S216
S
A
G
Q
L
A
L
S
G
R
N
V
P
V
Q
Chimpanzee
Pan troglodytes
XP_001160851
1020
115010
S216
S
S
G
Q
L
A
L
S
G
R
N
V
P
V
Q
Rhesus Macaque
Macaca mulatta
XP_001100859
1050
117053
S225
N
A
G
Q
L
G
L
S
D
E
K
D
R
E
S
Dog
Lupus familis
XP_851549
1015
114411
H216
N
A
G
Q
L
A
L
H
K
N
N
V
S
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAV2
1057
118393
N225
K
F
G
Q
L
G
L
N
D
E
N
D
R
Y
V
Rat
Rattus norvegicus
Q5PQN1
1057
118521
N225
K
F
G
Q
L
G
L
N
D
E
N
D
R
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231234
1056
118760
N225
K
F
G
Q
L
G
L
N
D
D
N
D
R
Y
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LYZ7
1502
167273
S356
G
M
L
R
K
L
S
S
G
S
A
L
A
F
R
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
M135
C
T
L
E
G
L
Q
M
V
V
R
R
C
H
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
38.9
73.3
N.A.
37.5
37.6
N.A.
N.A.
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.7
56.9
83
N.A.
57.7
57.5
N.A.
N.A.
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
40
60
N.A.
33.3
33.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
66.6
N.A.
40
40
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
41.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
34
0
0
0
0
12
0
12
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
45
12
0
45
0
0
12
% D
% Glu:
0
0
0
12
0
0
0
0
0
34
0
0
0
12
0
% E
% Phe:
0
34
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
78
0
12
45
0
0
34
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
0
0
12
0
0
0
12
0
12
0
0
0
0
% K
% Leu:
0
0
23
0
78
23
78
0
0
0
0
12
0
0
0
% L
% Met:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
0
0
0
34
0
12
67
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% P
% Gln:
0
0
0
78
0
0
12
0
0
0
0
0
0
0
34
% Q
% Arg:
0
0
0
12
0
0
0
0
0
23
12
12
45
0
12
% R
% Ser:
23
12
0
0
0
0
12
45
0
12
0
0
12
0
12
% S
% Thr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
12
0
34
0
23
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _