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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LOXHD1
All Species:
9.7
Human Site:
S668
Identified Species:
23.7
UniProt:
Q8IVV2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVV2
NP_001138944.1
1947
221947
S668
K
K
K
K
R
K
G
S
D
E
E
D
E
G
E
Chimpanzee
Pan troglodytes
XP_512115
1530
174171
V360
S
G
W
Y
L
D
R
V
L
V
R
E
E
G
Q
Rhesus Macaque
Macaca mulatta
XP_001090494
2080
237295
S669
K
K
K
K
R
K
G
S
D
E
E
E
E
G
E
Dog
Lupus familis
XP_547589
2230
254644
T918
K
K
K
K
K
K
K
T
H
T
T
R
R
M
R
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472229
2101
238944
Y680
S
R
V
Y
I
K
L
Y
G
E
K
S
D
T
I
Rat
Rattus norvegicus
NP_001099602
598
68072
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506257
1415
160192
S245
L
V
R
E
L
L
P
S
D
S
N
S
R
L
K
Chicken
Gallus gallus
XP_425221
2003
225332
V700
T
S
K
E
T
L
L
V
S
D
N
D
L
G
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920640
2206
250180
E978
K
K
S
K
K
K
S
E
D
D
D
E
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193389
1706
193109
V534
S
E
D
D
G
Q
I
V
R
E
L
V
P
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
86.3
75.9
N.A.
60.8
28.6
N.A.
51.7
36
N.A.
48.4
N.A.
N.A.
N.A.
N.A.
39.4
Protein Similarity:
100
77.5
89.1
80.7
N.A.
70.4
29.7
N.A.
62.4
54.7
N.A.
64.3
N.A.
N.A.
N.A.
N.A.
56.8
P-Site Identity:
100
13.3
93.3
33.3
N.A.
13.3
0
N.A.
13.3
20
N.A.
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
46.6
N.A.
33.3
0
N.A.
33.3
33.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
10
0
0
40
20
10
20
10
0
10
% D
% Glu:
0
10
0
20
0
0
0
10
0
40
20
30
40
10
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
0
20
0
10
0
0
0
0
40
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
40
40
40
40
20
50
10
0
0
0
10
0
0
0
10
% K
% Leu:
10
0
0
0
20
20
20
0
10
0
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
10
0
20
0
10
0
10
0
10
10
20
0
10
% R
% Ser:
30
10
10
0
0
0
10
30
10
10
0
20
0
0
0
% S
% Thr:
10
0
0
0
10
0
0
10
0
10
10
0
0
20
0
% T
% Val:
0
10
10
0
0
0
0
30
0
10
0
10
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _