KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LOXHD1
All Species:
13.94
Human Site:
T280
Identified Species:
34.07
UniProt:
Q8IVV2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVV2
NP_001138944.1
1947
221947
T280
G
M
A
R
Y
H
V
T
V
C
T
G
E
L
E
Chimpanzee
Pan troglodytes
XP_512115
1530
174171
V13
L
N
T
L
F
P
V
V
S
T
P
A
I
T
Y
Rhesus Macaque
Macaca mulatta
XP_001090494
2080
237295
T280
G
M
A
R
Y
R
V
T
V
C
T
G
E
L
E
Dog
Lupus familis
XP_547589
2230
254644
T529
G
M
A
R
Y
R
V
T
V
C
T
G
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472229
2101
238944
T301
T
A
I
T
Y
I
V
T
V
F
T
G
D
I
R
Rat
Rattus norvegicus
NP_001099602
598
68072
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506257
1415
160192
Chicken
Gallus gallus
XP_425221
2003
225332
A279
T
G
I
V
Y
N
V
A
V
V
T
G
D
I
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920640
2206
250180
T611
P
V
V
K
Y
R
V
T
V
Y
T
G
D
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193389
1706
193109
H187
M
K
R
I
R
I
G
H
D
G
S
G
A
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
86.3
75.9
N.A.
60.8
28.6
N.A.
51.7
36
N.A.
48.4
N.A.
N.A.
N.A.
N.A.
39.4
Protein Similarity:
100
77.5
89.1
80.7
N.A.
70.4
29.7
N.A.
62.4
54.7
N.A.
64.3
N.A.
N.A.
N.A.
N.A.
56.8
P-Site Identity:
100
6.6
93.3
93.3
N.A.
40
0
N.A.
0
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
53.3
0
N.A.
0
53.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
0
0
0
0
10
0
0
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
30
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
30
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
30
10
0
0
0
0
10
0
0
10
0
70
0
10
0
% G
% His:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
10
0
20
0
0
0
0
0
0
10
20
0
% I
% Lys:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
10
0
0
0
0
0
0
0
0
0
30
0
% L
% Met:
10
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
30
10
30
0
0
0
0
0
0
0
0
20
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% S
% Thr:
20
0
10
10
0
0
0
50
0
10
60
0
0
10
0
% T
% Val:
0
10
10
10
0
0
70
10
60
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
60
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _