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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LOXHD1
All Species:
16.06
Human Site:
Y431
Identified Species:
39.26
UniProt:
Q8IVV2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVV2
NP_001138944.1
1947
221947
Y431
S
R
V
Y
I
K
L
Y
G
D
K
S
D
T
I
Chimpanzee
Pan troglodytes
XP_512115
1530
174171
L151
L
K
K
F
P
W
S
L
W
V
W
T
T
D
L
Rhesus Macaque
Macaca mulatta
XP_001090494
2080
237295
Y431
S
R
V
Y
I
K
L
Y
G
D
K
S
D
T
I
Dog
Lupus familis
XP_547589
2230
254644
Y680
S
R
V
Y
I
K
L
Y
G
D
K
S
D
T
I
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472229
2101
238944
Y450
S
P
I
F
I
Q
I
Y
G
K
K
G
R
T
D
Rat
Rattus norvegicus
NP_001099602
598
68072
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506257
1415
160192
V36
V
V
T
V
T
G
D
V
R
G
A
G
T
D
A
Chicken
Gallus gallus
XP_425221
2003
225332
F424
A
G
T
D
A
T
I
F
F
Q
I
Y
G
D
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920640
2206
250180
Y762
S
K
V
F
V
K
L
Y
G
E
K
G
D
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193389
1706
193109
G325
D
G
S
G
P
G
A
G
W
F
L
D
H
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
86.3
75.9
N.A.
60.8
28.6
N.A.
51.7
36
N.A.
48.4
N.A.
N.A.
N.A.
N.A.
39.4
Protein Similarity:
100
77.5
89.1
80.7
N.A.
70.4
29.7
N.A.
62.4
54.7
N.A.
64.3
N.A.
N.A.
N.A.
N.A.
56.8
P-Site Identity:
100
0
100
100
N.A.
40
0
N.A.
0
0
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
66.6
0
N.A.
0
20
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
10
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
10
0
0
30
0
10
40
30
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
30
0
0
0
10
10
10
0
0
0
0
0
% F
% Gly:
0
20
0
10
0
20
0
10
50
10
0
30
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
40
0
20
0
0
0
10
0
0
10
30
% I
% Lys:
0
20
10
0
0
40
0
0
0
10
50
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
40
10
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
20
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
30
0
0
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
50
0
10
0
0
0
10
0
0
0
0
30
0
0
10
% S
% Thr:
0
0
20
0
10
10
0
0
0
0
0
10
20
50
0
% T
% Val:
10
10
40
10
10
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
20
0
10
0
0
0
0
% W
% Tyr:
0
0
0
30
0
0
0
50
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _