Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL17A All Species: 5.15
Human Site: S146 Identified Species: 7.56
UniProt: Q8IVW1 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVW1 NP_001034172.3 177 19388 S146 D S I L P H Q S P A W G P W G
Chimpanzee Pan troglodytes XP_001135548 177 19427 S146 D S I L P H Q S P A W G P W G
Rhesus Macaque Macaca mulatta XP_001105536 181 20660 H146 I T D K L G L H F L R H R N W
Dog Lupus familis XP_537606 181 20714 H146 I T D K L G L H S L R Q R N W
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P84082 181 20727 H146 I T D K L G L H S L R Q R N W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511637 208 22921 D146 C P A A P R R D G P S G L P P
Chicken Gallus gallus P49702 180 20461 Q146 L T D K L G L Q A L R S R T W
Frog Xenopus laevis P51643 181 20696 H146 I T D K L G L H S L R H R N W
Zebra Danio Brachydanio rerio NP_958912 181 20547 H146 I T D K L G L H S L R H R N W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61209 182 20669 H146 I T D K L G L H S L R N R N W
Honey Bee Apis mellifera XP_392990 182 20688 H146 I T D K L G L H S L R N R N W
Nematode Worm Caenorhab. elegans Q10943 181 20503 H146 V T D K L G L H S L R N R S W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 N146 I T D K L G L N S L R Q R H W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRC3 181 20574 H146 I T D K L G L H S L R Q R H W
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 H146 I T E K L G L H S I R N R P W
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S149 I T D K L G L S S L R Q R S W
Conservation
Percent
Protein Identity: 100 98.8 40.3 41.4 N.A. N.A. 41.4 N.A. 38.9 36.6 39.7 40.3 N.A. 41.2 41.2 38.6 N.A.
Protein Similarity: 100 99.4 52.4 54.7 N.A. N.A. 54.7 N.A. 49 50 52.4 53.5 N.A. 55.4 55.4 52.4 N.A.
P-Site Identity: 100 100 0 0 N.A. N.A. 0 N.A. 13.3 0 0 0 N.A. 0 0 0 N.A.
P-Site Similarity: 100 100 6.6 6.6 N.A. N.A. 6.6 N.A. 20 6.6 6.6 6.6 N.A. 6.6 6.6 6.6 N.A.
Percent
Protein Identity: N.A. 38.6 N.A. 38.1 36.4 42.1
Protein Similarity: N.A. 50.2 N.A. 50.2 51.9 52.9
P-Site Identity: N.A. 0 N.A. 0 0 6.6
P-Site Similarity: N.A. 13.3 N.A. 6.6 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 0 0 7 13 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 75 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 82 0 0 7 0 0 19 0 0 13 % G
% His: 0 0 0 0 0 13 0 63 0 0 0 19 0 13 0 % H
% Ile: 69 0 13 0 0 0 0 0 0 7 0 0 0 0 0 % I
% Lys: 0 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 13 82 0 82 0 0 75 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 25 0 44 0 % N
% Pro: 0 7 0 0 19 0 0 0 13 7 0 0 13 13 7 % P
% Gln: 0 0 0 0 0 0 13 7 0 0 0 32 0 0 0 % Q
% Arg: 0 0 0 0 0 7 7 0 0 0 82 0 82 0 0 % R
% Ser: 0 13 0 0 0 0 0 19 69 0 7 7 0 13 0 % S
% Thr: 0 82 0 0 0 0 0 0 0 0 0 0 0 7 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 82 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _