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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKL3
All Species:
11.52
Human Site:
S341
Identified Species:
19.49
UniProt:
Q8IVW4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVW4
NP_001107047.1
592
67514
S341
T
N
T
L
L
S
S
S
V
L
G
K
E
I
E
Chimpanzee
Pan troglodytes
XP_517934
592
67566
S341
T
N
T
L
L
S
S
S
V
L
G
K
E
I
E
Rhesus Macaque
Macaca mulatta
XP_001108660
592
67612
S341
T
N
T
L
L
S
S
S
V
L
G
K
E
I
E
Dog
Lupus familis
XP_850612
456
51739
K246
L
P
Q
V
Q
H
T
K
N
A
R
K
K
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLF2
595
67720
N341
T
N
T
L
L
Y
G
N
P
S
L
Y
G
K
E
Rat
Rattus norvegicus
Q9JM01
593
67534
N341
T
N
P
L
L
Y
G
N
P
T
L
Y
G
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512927
637
71445
L341
V
N
K
I
A
N
N
L
T
V
G
K
D
T
D
Chicken
Gallus gallus
P13863
303
34670
T93
D
L
K
K
Y
L
D
T
I
P
S
G
Q
Y
L
Frog
Xenopus laevis
P35567
302
34487
D92
M
D
L
K
K
Y
L
D
S
I
P
S
G
Q
Y
Zebra Danio
Brachydanio rerio
Q6AXJ9
350
40792
I140
L
I
T
K
H
Q
V
I
K
L
C
D
F
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
L87
F
E
F
L
S
M
D
L
K
K
Y
M
D
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784044
926
104004
T398
E
S
Q
K
K
S
S
T
I
A
S
T
S
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
D84
Y
L
V
F
E
Y
L
D
L
D
L
K
K
F
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
D84
Y
L
V
F
E
Y
L
D
L
D
L
K
K
H
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
67.7
N.A.
80.5
79
N.A.
57.7
25
24.3
31
N.A.
23.4
N.A.
N.A.
30.2
Protein Similarity:
100
99.8
99.6
72.1
N.A.
89.7
87.6
N.A.
68.9
34.9
35.6
43
N.A.
35.1
N.A.
N.A.
44
P-Site Identity:
100
100
100
6.6
N.A.
40
33.3
N.A.
20
0
0
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
46.6
40
N.A.
60
20
13.3
13.3
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
22.8
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
33.9
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
15
22
0
15
0
8
15
0
8
% D
% Glu:
8
8
0
0
15
0
0
0
0
0
0
0
22
0
36
% E
% Phe:
8
0
8
15
0
0
0
0
0
0
0
0
8
8
8
% F
% Gly:
0
0
0
0
0
0
15
0
0
0
29
8
22
8
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
8
0
0
0
8
15
8
0
0
0
22
0
% I
% Lys:
0
0
15
29
15
0
0
8
15
8
0
50
22
15
0
% K
% Leu:
15
22
8
43
36
8
22
15
15
29
29
0
0
0
15
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
15
% M
% Asn:
0
43
0
0
0
8
8
15
8
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
0
0
0
15
8
8
0
0
0
8
% P
% Gln:
0
0
15
0
8
8
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
8
29
29
22
8
8
15
8
8
8
0
% S
% Thr:
36
0
36
0
0
0
8
15
8
8
0
8
0
8
8
% T
% Val:
8
0
15
8
0
0
8
0
22
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
8
36
0
0
0
0
8
15
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _