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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKL3
All Species:
18.18
Human Site:
Y200
Identified Species:
30.77
UniProt:
Q8IVW4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVW4
NP_001107047.1
592
67514
Y200
E
M
A
T
G
N
P
Y
L
P
S
S
S
D
L
Chimpanzee
Pan troglodytes
XP_517934
592
67566
Y200
E
M
A
T
G
N
P
Y
L
P
S
S
S
D
L
Rhesus Macaque
Macaca mulatta
XP_001108660
592
67612
Y200
E
M
A
T
G
N
P
Y
L
P
S
S
S
D
L
Dog
Lupus familis
XP_850612
456
51739
N130
H
R
D
I
K
P
E
N
I
L
V
S
Q
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLF2
595
67720
F200
E
M
A
T
G
H
P
F
L
P
S
S
S
D
L
Rat
Rattus norvegicus
Q9JM01
593
67534
Y200
E
M
A
T
G
N
P
Y
L
P
S
S
S
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512927
637
71445
Y200
E
M
A
T
G
N
P
Y
L
P
S
S
S
D
L
Chicken
Gallus gallus
P13863
303
34670
Frog
Xenopus laevis
P35567
302
34487
Zebra Danio
Brachydanio rerio
Q6AXJ9
350
40792
K24
V
V
F
K
C
R
N
K
D
T
G
Q
I
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784044
926
104004
L201
E
M
L
T
G
E
P
L
F
P
G
D
S
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
67.7
N.A.
80.5
79
N.A.
57.7
25
24.3
31
N.A.
23.4
N.A.
N.A.
30.2
Protein Similarity:
100
99.8
99.6
72.1
N.A.
89.7
87.6
N.A.
68.9
34.9
35.6
43
N.A.
35.1
N.A.
N.A.
44
P-Site Identity:
100
100
100
6.6
N.A.
86.6
100
N.A.
100
0
0
0
N.A.
0
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
0
0
6.6
N.A.
0
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
22.8
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
33.9
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
43
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
0
0
8
0
50
0
% D
% Glu:
50
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
50
0
0
0
0
0
15
0
0
0
8
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
8
% I
% Lys:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
8
43
8
0
0
0
0
43
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
36
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
50
0
0
50
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
43
50
50
8
0
% S
% Thr:
0
0
0
50
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _