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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPNS2 All Species: 9.09
Human Site: S251 Identified Species: 18.18
UniProt: Q8IVW8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVW8 NP_001118230.1 549 58044 S251 L G Y I T G S S V K Q A A G D
Chimpanzee Pan troglodytes XP_001147063 528 56585 F235 V V A V L L L F L V V R E P P
Rhesus Macaque Macaca mulatta XP_001117725 578 61647 S280 L G Y I T G S S V K Q A A G D
Dog Lupus familis XP_848415 477 51731 H188 K Q A A G D W H W A L R V S P
Cat Felis silvestris
Mouse Mus musculus Q91VM4 549 58177 S251 L G Y I T G S S V K Q A A G D
Rat Rattus norvegicus Q2YDU8 528 56778 L234 G V L A V L L L F L V V Q E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510741 407 43118 Q118 G W E V V P A Q P S G S D L L
Chicken Gallus gallus XP_415740 403 43745 I114 L G S G L G Y I T G S S V K Q
Frog Xenopus laevis Q5XGK0 526 57788 I235 L L A V L L L I F V A E E P P
Zebra Danio Brachydanio rerio A2SWM2 504 54652 A215 A G G H W Y W A L R V S P M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GQQ0 605 65801 K261 L G Y I V G S K T A H L A N D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193605 553 60509 L255 L G Y I S G K L V A E L A G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.7 92.7 75.2 N.A. 95.9 49.7 N.A. 51.7 69 48 67.9 N.A. 37 N.A. N.A. 41.2
Protein Similarity: 100 62.6 93.4 79.5 N.A. 97.2 62.6 N.A. 56.8 71.4 61.2 75.9 N.A. 52.4 N.A. N.A. 56
P-Site Identity: 100 0 100 0 N.A. 100 0 N.A. 0 20 6.6 6.6 N.A. 53.3 N.A. N.A. 60
P-Site Similarity: 100 20 100 0 N.A. 100 0 N.A. 20 26.6 13.3 33.3 N.A. 53.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 25 17 0 0 9 9 0 25 9 25 42 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 42 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 9 9 17 9 0 % E
% Phe: 0 0 0 0 0 0 0 9 17 0 0 0 0 0 0 % F
% Gly: 17 59 9 9 9 50 0 0 0 9 9 0 0 34 0 % G
% His: 0 0 0 9 0 0 0 9 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 42 0 0 0 17 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 9 9 0 25 0 0 0 9 0 % K
% Leu: 59 9 9 0 25 25 25 17 17 9 9 17 0 9 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 9 0 0 9 0 0 0 9 17 34 % P
% Gln: 0 9 0 0 0 0 0 9 0 0 25 0 9 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 17 0 0 0 % R
% Ser: 0 0 9 0 9 0 34 25 0 9 9 25 0 9 0 % S
% Thr: 0 0 0 0 25 0 0 0 17 0 0 0 0 0 0 % T
% Val: 9 17 0 25 25 0 0 0 34 17 25 9 17 0 0 % V
% Trp: 0 9 0 0 9 0 17 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 42 0 0 9 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _