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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPNS2
All Species:
20.3
Human Site:
S266
Identified Species:
40.61
UniProt:
Q8IVW8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVW8
NP_001118230.1
549
58044
S266
W
H
W
A
L
R
V
S
P
V
L
G
M
I
T
Chimpanzee
Pan troglodytes
XP_001147063
528
56585
S250
R
G
A
V
E
R
H
S
D
L
P
P
L
N
P
Rhesus Macaque
Macaca mulatta
XP_001117725
578
61647
S295
W
H
W
A
L
R
V
S
P
V
L
G
M
I
T
Dog
Lupus familis
XP_848415
477
51731
T203
I
V
G
M
I
T
G
T
L
I
L
I
L
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM4
549
58177
S266
W
H
W
A
L
R
V
S
P
V
L
G
M
I
T
Rat
Rattus norvegicus
Q2YDU8
528
56778
H249
P
R
G
A
V
E
R
H
S
G
S
P
P
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510741
407
43118
F133
S
P
L
V
R
Q
Y
F
W
L
L
V
L
S
R
Chicken
Gallus gallus
XP_415740
403
43745
A129
V
A
G
D
W
H
W
A
L
R
V
S
P
L
L
Frog
Xenopus laevis
Q5XGK0
526
57788
T250
R
G
A
L
E
R
K
T
D
R
P
L
T
N
T
Zebra Danio
Brachydanio rerio
A2SWM2
504
54652
I230
G
L
T
A
G
T
L
I
L
I
F
V
S
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GQQ0
605
65801
T276
W
R
W
A
L
R
V
T
P
I
L
G
I
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193605
553
60509
T270
W
R
W
A
L
R
F
T
P
P
L
G
I
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.7
92.7
75.2
N.A.
95.9
49.7
N.A.
51.7
69
48
67.9
N.A.
37
N.A.
N.A.
41.2
Protein Similarity:
100
62.6
93.4
79.5
N.A.
97.2
62.6
N.A.
56.8
71.4
61.2
75.9
N.A.
52.4
N.A.
N.A.
56
P-Site Identity:
100
13.3
100
6.6
N.A.
100
6.6
N.A.
6.6
0
13.3
6.6
N.A.
60
N.A.
N.A.
53.3
P-Site Similarity:
100
26.6
100
40
N.A.
100
26.6
N.A.
26.6
20
20
20
N.A.
86.6
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
59
0
0
0
9
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
9
0
0
0
0
17
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
17
9
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
9
0
0
0
0
% F
% Gly:
9
17
25
0
9
0
9
0
0
9
0
42
0
0
0
% G
% His:
0
25
0
0
0
9
9
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
9
0
25
0
9
17
25
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
9
42
0
9
0
25
17
59
9
25
17
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
9
9
0
0
0
0
0
0
42
9
17
17
17
0
25
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
25
0
0
9
59
9
0
0
17
0
0
0
0
9
% R
% Ser:
9
0
0
0
0
0
0
34
9
0
9
9
9
9
9
% S
% Thr:
0
0
9
0
0
17
0
34
0
0
0
0
9
0
34
% T
% Val:
9
9
0
17
9
0
34
0
0
25
9
17
0
25
0
% V
% Trp:
42
0
42
0
9
0
9
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _