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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPNS2
All Species:
10.91
Human Site:
S489
Identified Species:
21.82
UniProt:
Q8IVW8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVW8
NP_001118230.1
549
58044
S489
I
S
D
L
I
R
Q
S
T
K
D
S
P
L
W
Chimpanzee
Pan troglodytes
XP_001147063
528
56585
L473
L
C
A
F
V
G
A
L
G
G
A
A
F
L
G
Rhesus Macaque
Macaca mulatta
XP_001117725
578
61647
S518
I
S
D
L
I
R
Q
S
T
K
D
S
P
L
W
Dog
Lupus familis
XP_848415
477
51731
E425
T
K
D
S
P
L
W
E
F
L
S
L
G
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM4
549
58177
S489
I
S
D
L
I
R
Q
S
T
K
D
S
P
L
W
Rat
Rattus norvegicus
Q2YDU8
528
56778
G471
L
M
L
C
A
F
V
G
A
L
G
G
A
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510741
407
43118
F355
A
I
F
I
C
L
V
F
V
A
A
K
G
S
I
Chicken
Gallus gallus
XP_415740
403
43745
D351
Y
L
I
G
F
I
S
D
L
I
R
Q
S
T
K
Frog
Xenopus laevis
Q5XGK0
526
57788
G472
C
A
F
V
G
V
I
G
G
G
F
F
L
T
T
Zebra Danio
Brachydanio rerio
A2SWM2
504
54652
L452
T
S
E
I
W
Q
F
L
S
L
G
Y
A
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GQQ0
605
65801
T534
A
T
T
S
L
M
E
T
A
R
S
S
A
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193605
553
60509
E492
H
E
D
S
E
S
T
E
A
K
Y
T
S
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.7
92.7
75.2
N.A.
95.9
49.7
N.A.
51.7
69
48
67.9
N.A.
37
N.A.
N.A.
41.2
Protein Similarity:
100
62.6
93.4
79.5
N.A.
97.2
62.6
N.A.
56.8
71.4
61.2
75.9
N.A.
52.4
N.A.
N.A.
56
P-Site Identity:
100
6.6
100
6.6
N.A.
100
0
N.A.
0
0
0
13.3
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
26.6
100
6.6
N.A.
100
13.3
N.A.
6.6
0
13.3
40
N.A.
40
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
0
9
0
9
0
25
9
17
9
25
9
9
% A
% Cys:
9
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
0
0
0
0
9
0
0
25
0
0
0
0
% D
% Glu:
0
9
9
0
9
0
9
17
0
0
0
0
0
0
0
% E
% Phe:
0
0
17
9
9
9
9
9
9
0
9
9
9
0
9
% F
% Gly:
0
0
0
9
9
9
0
17
17
17
17
9
17
0
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
9
9
17
25
9
9
0
0
9
0
0
0
0
17
% I
% Lys:
0
9
0
0
0
0
0
0
0
34
0
9
0
0
9
% K
% Leu:
17
9
9
25
9
17
0
17
9
25
0
9
9
50
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
25
0
0
% P
% Gln:
0
0
0
0
0
9
25
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
25
0
0
0
9
9
0
0
0
0
% R
% Ser:
0
34
0
25
0
9
9
25
9
0
17
34
17
17
0
% S
% Thr:
17
9
9
0
0
0
9
9
25
0
0
9
0
17
9
% T
% Val:
0
0
0
9
9
9
17
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
25
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _