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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPNS2 All Species: 10.3
Human Site: T392 Identified Species: 20.61
UniProt: Q8IVW8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVW8 NP_001118230.1 549 58044 T392 T R W C R L K T Q R A D P L V
Chimpanzee Pan troglodytes XP_001147063 528 56585 C376 F L F L S L A C A R G S I V A
Rhesus Macaque Macaca mulatta XP_001117725 578 61647 T421 T R W C R L K T Q R A D P L V
Dog Lupus familis XP_848415 477 51731 C328 Q R A D P L V C A V G M L G S
Cat Felis silvestris
Mouse Mus musculus Q91VM4 549 58177 T392 T R W C R L R T Q R A D P L V
Rat Rattus norvegicus Q2YDU8 528 56778 L374 S P F L F L S L A C A R G S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510741 407 43118 S258 R N R S Y V F S S L A T S A V
Chicken Gallus gallus XP_415740 403 43745 W254 T G A G A T K W C R L K T Q R
Frog Xenopus laevis Q5XGK0 526 57788 A375 L F L S L A F A D T S L V A T
Zebra Danio Brachydanio rerio A2SWM2 504 54652 V355 A D P L V C A V S M L G S A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GQQ0 605 65801 L437 A L I F F G Q L A L N L N W A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193605 553 60509 C395 D R A D P L V C A A G M L L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.7 92.7 75.2 N.A. 95.9 49.7 N.A. 51.7 69 48 67.9 N.A. 37 N.A. N.A. 41.2
Protein Similarity: 100 62.6 93.4 79.5 N.A. 97.2 62.6 N.A. 56.8 71.4 61.2 75.9 N.A. 52.4 N.A. N.A. 56
P-Site Identity: 100 13.3 100 13.3 N.A. 93.3 13.3 N.A. 13.3 20 0 0 N.A. 0 N.A. N.A. 20
P-Site Similarity: 100 26.6 100 13.3 N.A. 100 33.3 N.A. 26.6 20 6.6 6.6 N.A. 6.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 25 0 9 9 17 9 42 9 42 0 0 25 17 % A
% Cys: 0 0 0 25 0 9 0 25 9 9 0 0 0 0 0 % C
% Asp: 9 9 0 17 0 0 0 0 9 0 0 25 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 9 17 9 17 0 17 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 9 0 0 0 0 25 9 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 17 % I
% Lys: 0 0 0 0 0 0 25 0 0 0 0 9 0 0 0 % K
% Leu: 9 17 9 25 9 59 0 17 0 17 17 17 17 34 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 17 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 9 0 9 0 0 % N
% Pro: 0 9 9 0 17 0 0 0 0 0 0 0 25 0 0 % P
% Gln: 9 0 0 0 0 0 9 0 25 0 0 0 0 9 0 % Q
% Arg: 9 42 9 0 25 0 9 0 0 42 0 9 0 0 9 % R
% Ser: 9 0 0 17 9 0 9 9 17 0 9 9 17 9 17 % S
% Thr: 34 0 0 0 0 9 0 25 0 9 0 9 9 0 9 % T
% Val: 0 0 0 0 9 9 17 9 0 9 0 0 9 9 34 % V
% Trp: 0 0 25 0 0 0 0 9 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _