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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPNS2 All Species: 4.55
Human Site: T74 Identified Species: 9.09
UniProt: Q8IVW8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IVW8 NP_001118230.1 549 58044 T74 A P T G P P G T P G T P G C A
Chimpanzee Pan troglodytes XP_001147063 528 56585 L65 S A L I V A V L C Y I N L L N
Rhesus Macaque Macaca mulatta XP_001117725 578 61647 T103 A P T G P P G T P G T P G C A
Dog Lupus familis XP_848415 477 51731 F20 L L D I Q Q H F G V K D R G A
Cat Felis silvestris
Mouse Mus musculus Q91VM4 549 58177 I74 V P S G L P S I P S T P G C A
Rat Rattus norvegicus Q2YDU8 528 56778 L65 S T L I V V V L C Y I N L L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510741 407 43118
Chicken Gallus gallus XP_415740 403 43745
Frog Xenopus laevis Q5XGK0 526 57788 F66 V I I V I I L F Y I N L L N Y
Zebra Danio Brachydanio rerio A2SWM2 504 54652 A47 P G Q K F H A A L L R C R T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GQQ0 605 65801 P86 P H H H H H H P L G E H H H I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193605 553 60509 N76 P V N G I E G N V P N V K T D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.7 92.7 75.2 N.A. 95.9 49.7 N.A. 51.7 69 48 67.9 N.A. 37 N.A. N.A. 41.2
Protein Similarity: 100 62.6 93.4 79.5 N.A. 97.2 62.6 N.A. 56.8 71.4 61.2 75.9 N.A. 52.4 N.A. N.A. 56
P-Site Identity: 100 0 100 6.6 N.A. 60 0 N.A. 0 0 0 0 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 6.6 100 6.6 N.A. 66.6 6.6 N.A. 0 0 0 0 N.A. 6.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 0 9 9 9 0 0 0 0 0 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 17 0 0 9 0 25 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 9 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 9 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 34 0 0 25 0 9 25 0 0 25 9 0 % G
% His: 0 9 9 9 9 17 17 0 0 0 0 9 9 9 0 % H
% Ile: 0 9 9 25 17 9 0 9 0 9 17 0 0 0 9 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 9 0 9 0 0 % K
% Leu: 9 9 17 0 9 0 9 17 17 9 0 9 25 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 0 0 17 17 0 9 17 % N
% Pro: 25 25 0 0 17 25 0 9 25 9 0 25 0 0 9 % P
% Gln: 0 0 9 0 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 0 17 0 0 % R
% Ser: 17 0 9 0 0 0 9 0 0 9 0 0 0 0 0 % S
% Thr: 0 9 17 0 0 0 0 17 0 0 25 0 0 17 0 % T
% Val: 17 9 0 9 17 9 17 0 9 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 17 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _