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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAH3
All Species:
15.76
Human Site:
S48
Identified Species:
28.89
UniProt:
Q8IW03
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW03
NP_942146.2
269
30660
S48
T
H
N
L
K
Y
V
S
S
R
R
A
V
T
Q
Chimpanzee
Pan troglodytes
XP_522672
412
46152
S191
T
H
N
L
K
Y
V
S
S
R
R
A
V
T
Q
Rhesus Macaque
Macaca mulatta
XP_001096384
369
41398
S148
T
H
N
L
K
Y
V
S
S
R
R
A
V
T
Q
Dog
Lupus familis
XP_542573
247
28069
H46
E
Q
G
N
F
P
P
H
H
L
T
H
H
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q06986
325
34739
T114
Q
K
L
S
C
C
P
T
C
R
G
A
L
T
P
Rat
Rattus norvegicus
Q8R4T2
325
34681
T114
Q
K
L
S
C
C
P
T
C
R
G
A
L
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514000
253
28753
P48
T
R
N
R
K
P
V
P
A
R
R
P
V
A
Q
Chicken
Gallus gallus
XP_417044
242
27190
P48
T
H
S
L
K
Y
A
P
T
R
C
V
V
A
Q
Frog
Xenopus laevis
Q9I8X5
313
34081
T102
Q
K
L
S
C
C
P
T
C
R
A
S
L
T
P
Zebra Danio
Brachydanio rerio
Q7SYL3
331
34475
Q104
L
P
P
I
L
Q
C
Q
A
G
H
L
V
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21461
314
33689
T106
S
K
L
T
C
C
P
T
C
R
G
P
L
A
N
Honey Bee
Apis mellifera
XP_394284
279
30558
T71
P
K
L
N
C
C
P
T
C
R
G
P
L
G
N
Nematode Worm
Caenorhab. elegans
Q965X6
339
37641
E89
A
E
I
L
S
V
F
E
C
P
V
C
L
E
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.5
71.2
81.4
N.A.
35.3
35.3
N.A.
78.4
74.7
33.2
36.5
N.A.
35.3
39.4
32.4
N.A.
Protein Similarity:
100
64.8
71.5
84.3
N.A.
46.4
46.4
N.A.
82.5
80.6
44.4
48
N.A.
48.4
52.3
47.4
N.A.
P-Site Identity:
100
100
100
0
N.A.
20
20
N.A.
53.3
53.3
13.3
6.6
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
33.3
33.3
N.A.
60
66.6
33.3
20
N.A.
26.6
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
16
0
8
39
0
24
0
% A
% Cys:
0
0
0
0
39
39
8
0
47
0
8
8
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
31
0
0
8
0
% G
% His:
0
31
0
0
0
0
0
8
8
0
8
8
8
8
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
39
0
0
39
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
39
39
8
0
0
0
0
8
0
8
47
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
31
16
0
0
0
0
0
0
0
0
0
0
24
% N
% Pro:
8
8
8
0
0
16
47
16
0
8
0
24
0
0
24
% P
% Gln:
24
8
0
0
0
8
0
8
0
0
0
0
0
0
39
% Q
% Arg:
0
8
0
8
0
0
0
0
0
77
31
0
0
0
8
% R
% Ser:
8
0
8
24
8
0
0
24
24
0
0
8
0
0
0
% S
% Thr:
39
0
0
8
0
0
0
39
8
0
8
0
0
47
0
% T
% Val:
0
0
0
0
0
8
31
0
0
0
8
8
47
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _