KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APLF
All Species:
0
Human Site:
S196
Identified Species:
0
UniProt:
Q8IW19
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW19
NP_775816.1
511
56956
S196
W
M
L
A
E
H
L
S
D
Q
N
L
S
V
P
Chimpanzee
Pan troglodytes
XP_515525
303
34195
K15
K
E
E
I
C
E
D
K
T
Q
L
N
T
T
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538525
510
57035
P195
A
W
M
L
T
E
D
P
S
D
Q
N
R
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D842
499
54950
A188
Q
R
K
R
I
L
P
A
W
M
L
A
E
S
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514287
555
61656
Q224
I
L
P
A
W
M
L
Q
E
D
L
N
A
P
S
Chicken
Gallus gallus
XP_419335
514
57457
L191
W
M
L
E
K
D
L
L
V
P
K
I
S
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099159
262
29285
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JR14
255
27987
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788055
674
74378
Q305
Q
A
K
K
T
P
S
Q
A
K
A
R
A
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.9
N.A.
72.2
N.A.
60
N.A.
N.A.
41.2
44.7
N.A.
23.4
N.A.
21.3
N.A.
N.A.
28.1
Protein Similarity:
100
58.9
N.A.
81.4
N.A.
74.7
N.A.
N.A.
57.2
61.8
N.A.
33
N.A.
31.5
N.A.
N.A.
43.7
P-Site Identity:
100
6.6
N.A.
0
N.A.
0
N.A.
N.A.
13.3
40
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
13.3
N.A.
6.6
N.A.
6.6
N.A.
N.A.
33.3
53.3
N.A.
0
N.A.
0
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
23
0
0
0
12
12
0
12
12
23
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
23
0
12
23
0
0
0
0
0
% D
% Glu:
0
12
12
12
12
23
0
0
12
0
0
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
12
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
12
0
23
12
12
0
0
12
0
12
12
0
0
0
12
% K
% Leu:
0
12
23
12
0
12
34
12
0
0
34
12
0
0
12
% L
% Met:
0
23
12
0
0
12
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
34
0
0
0
% N
% Pro:
0
0
12
0
0
12
12
12
0
12
0
0
0
12
23
% P
% Gln:
23
0
0
0
0
0
0
23
0
23
12
0
0
0
12
% Q
% Arg:
0
12
0
12
0
0
0
0
0
0
0
12
12
12
0
% R
% Ser:
0
0
0
0
0
0
12
12
12
0
0
0
23
23
12
% S
% Thr:
0
0
0
0
23
0
0
0
12
0
0
0
12
12
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
12
% V
% Trp:
23
12
0
0
12
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _