KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPKAPK5
All Species:
24.85
Human Site:
T294
Identified Species:
45.56
UniProt:
Q8IW41
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW41
NP_003659.2
473
54220
T294
V
K
P
E
E
R
L
T
I
E
G
V
L
D
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102910
666
74053
T489
V
K
P
E
E
R
L
T
I
E
G
V
L
D
H
Dog
Lupus familis
XP_534678
804
89494
T625
V
K
P
E
E
R
L
T
I
E
G
V
L
D
H
Cat
Felis silvestris
Mouse
Mus musculus
O54992
473
54134
T294
V
K
P
E
E
R
L
T
I
E
G
V
L
D
H
Rat
Rattus norvegicus
Q66H84
384
43204
S246
C
G
F
P
P
F
Y
S
N
T
G
Q
A
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521063
278
31941
N146
A
H
A
E
Q
L
A
N
M
R
I
Q
D
L
K
Chicken
Gallus gallus
Q5F3L1
789
89022
V335
V
I
R
D
E
L
D
V
S
N
F
A
E
E
F
Frog
Xenopus laevis
NP_001085020
377
43533
S245
C
G
Y
P
P
F
Y
S
N
H
G
F
A
I
S
Zebra Danio
Brachydanio rerio
NP_001002336
471
53898
T294
V
K
P
E
E
R
L
T
I
E
G
V
L
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49071
359
41383
I227
Y
S
N
H
G
L
A
I
S
P
G
M
K
N
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500006
366
41523
Q234
K
A
K
I
K
S
G
Q
Y
T
F
P
S
P
E
Sea Urchin
Strong. purpuratus
XP_001194739
473
54175
T295
V
D
P
T
E
R
L
T
I
E
E
L
C
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZV15
583
64702
T382
R
D
P
K
K
R
M
T
T
H
E
V
L
C
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
70.7
58
N.A.
97.2
34.4
N.A.
57.2
21.1
34
87
N.A.
32.3
N.A.
34.6
56
Protein Similarity:
100
N.A.
70.7
58.3
N.A.
98.7
52.8
N.A.
58.1
35.3
52
94.2
N.A.
49.2
N.A.
52.4
72.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
6.6
13.3
6.6
93.3
N.A.
6.6
N.A.
0
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
20
26.6
13.3
93.3
N.A.
20
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
16
0
0
0
0
8
16
8
0
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
16
0
8
0
0
8
0
0
0
0
0
8
31
0
% D
% Glu:
0
0
0
47
54
0
0
0
0
47
16
0
8
8
8
% E
% Phe:
0
0
8
0
0
16
0
0
0
0
16
8
0
0
8
% F
% Gly:
0
16
0
0
8
0
8
0
0
0
62
0
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
16
0
0
0
0
54
% H
% Ile:
0
8
0
8
0
0
0
8
47
0
8
0
0
16
0
% I
% Lys:
8
39
8
8
16
0
0
0
0
0
0
0
8
0
8
% K
% Leu:
0
0
0
0
0
24
47
0
0
0
0
8
47
8
0
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
16
8
0
0
0
8
0
% N
% Pro:
0
0
54
16
16
0
0
0
0
8
0
8
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
16
0
0
0
% Q
% Arg:
8
0
8
0
0
54
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
8
0
16
16
0
0
0
8
8
16
% S
% Thr:
0
0
0
8
0
0
0
54
8
16
0
0
0
0
0
% T
% Val:
54
0
0
0
0
0
0
8
0
0
0
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
16
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _