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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
23.33
Human Site:
S224
Identified Species:
39.49
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
S224
V
L
R
G
P
M
D
S
D
D
S
H
G
S
V
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
S224
V
L
R
G
P
M
D
S
D
D
S
H
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
S224
V
L
R
G
P
V
D
S
D
D
R
H
G
S
V
Dog
Lupus familis
XP_849113
379
40113
G256
V
L
S
H
Q
V
D
G
S
D
H
H
E
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
S220
V
L
S
S
P
M
D
S
N
D
L
K
G
S
T
Rat
Rattus norvegicus
NP_001101872
327
34944
T204
V
L
S
S
P
M
D
T
S
N
H
S
G
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
S503
M
L
R
D
P
V
D
S
S
D
H
H
G
C
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
S301
M
H
H
E
P
L
D
S
S
D
H
K
R
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
A188
Q
P
T
P
M
V
K
A
N
D
V
K
H
L
A
Nematode Worm
Caenorhab. elegans
P32740
307
33871
S184
Q
H
L
A
A
E
L
S
R
K
M
N
V
T
I
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
P211
V
V
G
S
D
V
N
P
A
E
P
Q
T
D
V
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
D239
V
L
N
C
E
V
N
D
Q
D
A
H
G
Q
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
E240
V
L
N
C
E
V
D
E
Q
N
A
E
D
Q
L
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
S199
A
I
G
K
K
G
D
S
H
S
E
M
G
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
100
86.6
40
N.A.
60
53.3
N.A.
N.A.
60
N.A.
33.3
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
100
93.3
53.3
N.A.
66.6
66.6
N.A.
N.A.
73.3
N.A.
46.6
N.A.
N.A.
26.6
26.6
40
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
33.3
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
60
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
8
8
0
15
0
0
8
15
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
8
0
72
8
22
65
0
0
8
8
0
% D
% Glu:
0
0
0
8
15
8
0
8
0
8
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
22
0
8
0
8
0
0
0
0
58
0
0
% G
% His:
0
15
8
8
0
0
0
0
8
0
29
43
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
8
0
8
0
0
8
0
22
0
0
0
% K
% Leu:
0
65
8
0
0
8
8
0
0
0
8
0
0
8
22
% L
% Met:
15
0
0
0
8
29
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
15
0
0
0
15
0
15
15
0
8
0
0
0
% N
% Pro:
0
8
0
8
50
0
0
8
0
0
8
0
0
0
0
% P
% Gln:
15
0
0
0
8
0
0
0
15
0
0
8
0
15
0
% Q
% Arg:
0
0
29
0
0
0
0
0
8
0
8
0
8
0
0
% R
% Ser:
0
0
22
22
0
0
0
58
29
8
15
8
0
50
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
0
0
8
8
8
% T
% Val:
65
8
0
0
0
50
0
0
0
0
8
0
8
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _