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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
40.61
Human Site:
S253
Identified Species:
68.72
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
S253
K
G
E
R
D
I
L
S
N
G
Q
Q
V
L
V
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
S253
K
G
E
R
D
I
L
S
N
G
Q
Q
V
L
V
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
S253
K
G
E
R
D
I
L
S
N
G
Q
Q
V
L
V
Dog
Lupus familis
XP_849113
379
40113
S285
K
G
E
R
D
V
I
S
D
G
K
Q
V
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
S249
K
G
E
Q
D
L
I
S
N
G
Q
Q
V
L
V
Rat
Rattus norvegicus
NP_001101872
327
34944
S233
K
G
E
Q
D
L
I
S
N
G
Q
Q
V
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
S532
K
G
E
R
D
L
I
S
D
G
E
K
V
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
T330
K
G
E
E
D
I
I
T
D
G
K
N
I
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
H217
K
D
V
I
A
D
G
H
K
G
T
E
A
V
S
Nematode Worm
Caenorhab. elegans
P32740
307
33871
E213
E
V
S
K
C
S
T
E
S
S
L
R
R
C
G
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
S240
K
G
A
N
D
I
I
S
D
G
H
N
V
L
V
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
S268
K
G
K
C
D
L
I
S
D
G
E
I
V
K
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
S269
K
G
K
S
D
L
I
S
N
G
E
T
V
K
S
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
D228
S
D
K
I
F
S
P
D
S
E
K
D
M
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
100
100
66.6
N.A.
80
80
N.A.
N.A.
66.6
N.A.
46.6
N.A.
N.A.
13.3
0
60
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
26.6
26.6
73.3
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
40
N.A.
N.A.
46.6
6.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
15
0
0
79
8
0
8
36
0
0
8
0
0
0
% D
% Glu:
8
0
58
8
0
0
0
8
0
8
22
8
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
79
0
0
0
0
8
0
0
86
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
15
0
36
58
0
0
0
0
8
8
0
0
% I
% Lys:
86
0
22
8
0
0
0
0
8
0
22
8
0
15
0
% K
% Leu:
0
0
0
0
0
36
22
0
0
0
8
0
0
72
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
43
0
0
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
0
0
36
43
0
0
0
% Q
% Arg:
0
0
0
36
0
0
0
0
0
0
0
8
8
0
0
% R
% Ser:
8
0
8
8
0
15
0
72
15
8
0
0
0
0
22
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
8
8
0
0
15
% T
% Val:
0
8
8
0
0
8
0
0
0
0
0
0
72
8
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _