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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
24.55
Human Site:
S300
Identified Species:
41.54
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
S300
P
Q
K
T
N
G
S
S
P
L
L
V
A
A
F
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
S300
P
E
K
T
N
G
S
S
P
L
L
V
A
A
F
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
S300
P
E
K
T
N
G
S
S
P
L
L
V
A
A
F
Dog
Lupus familis
XP_849113
379
40113
S332
P
E
K
T
N
G
S
S
P
L
L
L
A
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
S296
P
E
K
T
N
G
S
S
P
L
L
V
A
A
W
Rat
Rattus norvegicus
NP_001101872
327
34944
S280
P
E
K
T
N
G
S
S
P
L
L
V
A
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
N579
A
E
K
T
N
G
Q
N
P
F
L
V
A
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
N377
S
D
A
T
K
G
M
N
P
S
L
V
A
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
S263
G
N
N
E
S
A
L
S
P
P
I
A
A
S
Y
Nematode Worm
Caenorhab. elegans
P32740
307
33871
R261
I
A
S
S
W
L
V
R
T
A
G
R
R
A
F
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
G294
N
E
Y
L
K
I
F
G
P
T
L
C
A
A
Y
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
N320
N
L
I
I
S
P
T
N
P
T
M
L
G
C
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
N317
D
P
E
S
P
S
E
N
P
A
I
L
G
C
I
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
D291
K
P
L
K
N
W
V
D
Y
A
M
L
S
C
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
93.3
93.3
80
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
53.3
N.A.
N.A.
20
13.3
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
80
N.A.
60
N.A.
N.A.
46.6
20
40
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
0
0
0
22
0
8
72
72
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
22
0
% C
% Asp:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
50
8
8
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
43
% F
% Gly:
8
0
0
0
0
58
0
8
0
0
8
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
8
0
0
0
0
15
0
0
0
15
% I
% Lys:
8
0
50
8
15
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
8
0
8
8
0
0
43
65
29
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
15
0
0
0
0
% M
% Asn:
15
8
8
0
58
0
0
29
0
0
0
0
0
0
0
% N
% Pro:
43
15
0
0
8
8
0
0
86
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
8
0
8
15
15
8
43
50
0
8
0
0
8
8
0
% S
% Thr:
0
0
0
58
0
0
8
0
8
15
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
50
0
0
0
% V
% Trp:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _