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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
44.85
Human Site:
S331
Identified Species:
75.9
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
S331
H
G
R
S
T
T
T
S
D
M
I
A
E
V
G
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
S331
H
G
R
S
T
T
T
S
D
M
I
A
E
V
G
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
S331
H
G
R
S
T
T
T
S
D
M
I
A
E
V
G
Dog
Lupus familis
XP_849113
379
40113
T363
H
G
R
S
T
T
T
T
D
M
I
A
E
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
T327
Y
G
R
S
T
T
T
T
D
M
I
T
E
V
G
Rat
Rattus norvegicus
NP_001101872
327
34944
T311
Y
G
R
S
T
T
T
T
D
M
I
A
E
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
S610
L
G
R
S
M
T
A
S
D
M
V
S
E
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
S408
H
G
R
S
T
T
T
S
D
M
I
Q
E
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
T294
K
Q
R
G
M
L
T
T
D
I
L
E
Q
I
Q
Nematode Worm
Caenorhab. elegans
P32740
307
33871
E292
P
K
L
V
R
D
V
E
T
R
E
M
K
D
T
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
T325
N
G
R
G
M
T
T
T
E
M
L
P
E
I
Q
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
T351
R
K
R
S
T
L
T
T
D
I
I
E
C
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
S348
H
K
R
S
T
L
T
S
D
I
I
E
C
L
G
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
T322
K
G
R
A
M
Q
T
T
D
L
N
D
R
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
N.A.
66.6
N.A.
80
N.A.
N.A.
20
0
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
80
N.A.
86.6
N.A.
N.A.
53.3
6.6
73.3
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
46.6
N.A.
N.A.
60
40
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
0
0
36
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
86
0
0
8
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
8
22
65
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
72
0
15
0
0
0
0
0
0
0
0
0
0
72
% G
% His:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
22
65
0
0
29
0
% I
% Lys:
15
22
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
8
0
0
22
0
0
0
8
15
0
0
15
0
% L
% Met:
0
0
0
0
29
0
0
0
0
65
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
8
8
0
15
% Q
% Arg:
8
0
93
0
8
0
0
0
0
8
0
0
8
0
0
% R
% Ser:
0
0
0
72
0
0
0
43
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
65
65
86
50
8
0
0
8
0
0
8
% T
% Val:
0
0
0
8
0
0
8
0
0
0
8
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _