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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
18.18
Human Site:
S46
Identified Species:
30.77
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
S46
F
S
L
R
K
A
H
S
I
K
D
M
E
N
T
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
S46
F
S
L
R
K
A
H
S
I
K
D
M
E
N
T
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
S46
F
S
L
R
K
V
H
S
I
K
D
M
E
N
T
Dog
Lupus familis
XP_849113
379
40113
S78
F
S
L
H
K
A
H
S
V
E
D
M
E
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
V57
F
Q
L
V
R
N
I
V
P
A
L
T
S
K
K
Rat
Rattus norvegicus
NP_001101872
327
34944
K48
V
P
A
L
T
S
K
K
H
K
G
Q
D
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
T325
F
S
L
H
R
N
H
T
L
K
D
M
E
N
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
G123
I
E
R
S
F
S
L
G
T
S
G
M
D
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
A46
G
S
L
E
Y
T
G
A
P
Y
Y
A
A
M
S
Nematode Worm
Caenorhab. elegans
P32740
307
33871
L46
A
A
S
S
A
S
R
L
G
A
D
L
I
H
I
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
D52
R
S
I
V
P
S
L
D
F
T
K
H
K
G
Q
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
G48
R
G
D
N
R
M
Q
G
S
K
F
E
A
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
S46
S
P
I
I
R
A
M
S
S
T
S
E
A
D
A
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
F50
D
Y
T
G
A
P
Y
F
S
A
N
A
T
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
100
93.3
80
N.A.
13.3
6.6
N.A.
N.A.
60
N.A.
13.3
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
20
20
N.A.
N.A.
80
N.A.
26.6
N.A.
N.A.
26.6
33.3
26.6
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
15
29
0
8
0
22
0
15
22
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
8
0
0
43
0
15
15
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
8
0
15
36
0
0
% E
% Phe:
43
0
0
0
8
0
0
8
8
0
8
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
8
15
8
0
15
0
0
15
0
% G
% His:
0
0
0
15
0
0
36
0
8
0
0
8
0
8
0
% H
% Ile:
8
0
15
8
0
0
8
0
22
0
0
0
8
0
15
% I
% Lys:
0
0
0
0
29
0
8
8
0
43
8
0
8
8
8
% K
% Leu:
0
0
50
8
0
0
15
8
8
0
8
8
0
0
8
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
43
0
8
0
% M
% Asn:
0
0
0
8
0
15
0
0
0
0
8
0
0
43
0
% N
% Pro:
0
15
0
0
8
8
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
8
% Q
% Arg:
15
0
8
22
29
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
8
50
8
15
0
29
0
36
22
8
8
0
8
0
15
% S
% Thr:
0
0
8
0
8
8
0
8
8
15
0
8
8
0
29
% T
% Val:
8
0
0
15
0
8
0
8
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
8
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _