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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
22.12
Human Site:
S65
Identified Species:
37.44
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
S65
R
N
I
I
P
P
L
S
S
T
K
H
K
G
Q
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
S65
R
N
I
I
P
P
L
S
S
T
K
H
K
G
Q
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
S65
R
N
I
I
P
P
L
S
S
T
K
H
K
G
Q
Dog
Lupus familis
XP_849113
379
40113
T97
R
N
I
I
P
P
L
T
T
K
K
H
K
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
G76
D
G
R
I
G
I
V
G
G
C
Q
E
Y
T
G
Rat
Rattus norvegicus
NP_001101872
327
34944
G67
G
G
C
Q
E
Y
T
G
A
P
Y
F
A
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
T344
R
N
V
I
P
P
L
T
G
K
R
H
K
G
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
T142
R
N
T
I
P
P
L
T
S
K
K
H
K
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
F65
G
C
D
L
V
H
I
F
C
V
K
D
A
S
F
Nematode Worm
Caenorhab. elegans
P32740
307
33871
G65
D
A
A
Q
V
I
K
G
Y
S
P
D
L
I
V
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
E71
A
T
I
G
G
C
R
E
Y
T
G
A
P
Y
F
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
D67
R
A
I
T
P
V
F
D
P
N
R
H
K
G
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
D65
R
T
V
T
P
S
L
D
L
K
R
H
K
G
Q
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
Y69
L
T
H
V
I
C
E
Y
N
A
G
T
V
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
100
100
80
N.A.
6.6
6.6
N.A.
N.A.
66.6
N.A.
80
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
20
13.3
N.A.
N.A.
86.6
N.A.
86.6
N.A.
N.A.
20
6.6
13.3
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
46.6
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
0
0
0
0
8
8
0
8
15
0
0
% A
% Cys:
0
8
8
0
0
15
0
0
8
8
0
0
0
0
0
% C
% Asp:
15
0
8
0
0
0
0
15
0
0
0
15
0
0
0
% D
% Glu:
0
0
0
0
8
0
8
8
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
15
% F
% Gly:
15
15
0
8
15
0
0
22
15
0
15
0
0
65
8
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
58
0
0
0
% H
% Ile:
0
0
43
50
8
15
8
0
0
0
0
0
0
15
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
29
43
0
58
0
8
% K
% Leu:
8
0
0
8
0
0
50
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
43
0
0
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
58
43
0
0
8
8
8
0
8
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
0
0
8
0
0
0
58
% Q
% Arg:
58
0
8
0
0
0
8
0
0
0
22
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
22
29
8
0
0
0
8
0
% S
% Thr:
0
22
8
15
0
0
8
22
8
29
0
8
0
8
0
% T
% Val:
0
0
15
8
15
8
8
0
0
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
15
0
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _