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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARKD
All Species:
20.3
Human Site:
Y214
Identified Species:
34.36
UniProt:
Q8IW45
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW45
NP_060680.2
347
36576
Y214
H
V
E
F
S
R
L
Y
D
A
V
L
R
G
P
Chimpanzee
Pan troglodytes
XP_001138081
347
36596
Y214
H
M
E
F
S
R
L
Y
D
A
V
L
R
G
P
Rhesus Macaque
Macaca mulatta
XP_001083130
347
36777
Y214
H
M
E
F
S
R
L
Y
D
A
V
L
R
G
P
Dog
Lupus familis
XP_849113
379
40113
S246
H
V
E
F
N
R
L
S
E
A
V
L
S
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ42
343
36699
W210
H
V
E
F
S
R
L
W
E
A
V
L
S
S
P
Rat
Rattus norvegicus
NP_001101872
327
34944
W194
H
V
E
F
S
R
L
W
D
A
V
L
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416954
626
69229
Y493
Y
M
E
F
S
R
L
Y
E
A
M
L
R
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103590
424
46535
Y291
F
M
E
F
T
R
L
Y
E
A
M
H
H
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623353
329
36035
K178
L
V
K
G
V
L
D
K
N
V
Q
P
T
P
M
Nematode Worm
Caenorhab. elegans
P32740
307
33871
S174
V
L
N
V
R
N
N
S
Q
L
Q
H
L
A
A
Sea Urchin
Strong. purpuratus
XP_791028
343
37314
F201
V
V
E
F
K
H
L
F
K
S
V
V
G
S
D
Poplar Tree
Populus trichocarpa
XP_002312747
368
40017
V229
V
N
E
Y
K
R
L
V
Q
K
V
L
N
C
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568369
365
39251
V230
V
N
E
Y
K
R
L
V
Q
K
V
L
N
C
E
Baker's Yeast
Sacchar. cerevisiae
P36059
337
37339
L189
N
V
V
E
F
K
R
L
C
D
A
I
G
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
70.7
N.A.
80.1
75.7
N.A.
N.A.
42.8
N.A.
52.3
N.A.
N.A.
41.7
36.5
48.9
Protein Similarity:
100
99.1
95
80.2
N.A.
88.1
85.5
N.A.
N.A.
50.7
N.A.
64.8
N.A.
N.A.
59.3
51.8
68
P-Site Identity:
100
93.3
93.3
60
N.A.
73.3
80
N.A.
N.A.
66.6
N.A.
46.6
N.A.
N.A.
6.6
0
33.3
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
N.A.
73.3
N.A.
N.A.
20
6.6
53.3
Percent
Protein Identity:
41.3
N.A.
N.A.
41.3
38.9
N.A.
Protein Similarity:
59.7
N.A.
N.A.
58
59
N.A.
P-Site Identity:
33.3
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
58
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
15
0
% C
% Asp:
0
0
0
0
0
0
8
0
29
8
0
0
0
8
8
% D
% Glu:
0
0
79
8
0
0
0
0
29
0
0
0
0
8
15
% E
% Phe:
8
0
0
65
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
15
22
0
% G
% His:
43
0
0
0
0
8
0
0
0
0
0
15
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
22
8
0
8
8
15
0
0
0
8
8
% K
% Leu:
8
8
0
0
0
8
79
8
0
8
0
65
8
0
0
% L
% Met:
0
29
0
0
0
0
0
0
0
0
15
0
0
0
8
% M
% Asn:
8
15
8
0
8
8
8
0
8
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
50
% P
% Gln:
0
0
0
0
0
0
0
0
22
0
15
0
0
0
8
% Q
% Arg:
0
0
0
0
8
72
8
0
0
0
0
0
29
0
0
% R
% Ser:
0
0
0
0
43
0
0
15
0
8
0
0
22
22
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% T
% Val:
29
50
8
8
8
0
0
15
0
8
65
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
15
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _