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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf25
All Species:
22.73
Human Site:
S47
Identified Species:
55.56
UniProt:
Q8IW50
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW50
NP_671735.1
185
20400
S47
V
A
M
N
Y
K
P
S
P
L
Q
V
K
L
E
Chimpanzee
Pan troglodytes
XP_001161024
185
20399
S47
V
A
M
N
Y
K
P
S
P
L
Q
V
K
L
E
Rhesus Macaque
Macaca mulatta
XP_001088997
270
28968
S132
V
A
M
N
Y
K
P
S
P
L
Q
V
K
L
E
Dog
Lupus familis
XP_531979
185
20381
S47
V
A
M
N
Y
K
P
S
P
L
Q
V
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D772
157
17474
K27
D
C
D
A
R
E
E
K
Q
R
E
L
A
R
K
Rat
Rattus norvegicus
NP_001103086
157
17476
K27
D
C
D
A
R
E
E
K
Q
R
E
L
A
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511942
230
24741
P51
T
T
V
E
K
R
G
P
Y
I
M
A
R
P
P
Chicken
Gallus gallus
XP_001231783
185
20582
S47
V
A
M
N
Y
K
P
S
P
L
Q
V
K
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DC60
186
20685
S48
V
A
I
N
Y
K
P
S
P
L
Q
V
K
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178400
193
22137
K47
H
S
I
K
N
L
R
K
P
S
S
L
Q
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
68.1
100
N.A.
83.7
83.7
N.A.
36.5
95.1
N.A.
87
N.A.
N.A.
N.A.
N.A.
39.3
Protein Similarity:
100
100
68.1
100
N.A.
84.3
83.7
N.A.
50
96.7
N.A.
91.9
N.A.
N.A.
N.A.
N.A.
55.4
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
0
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
26.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
20
0
0
0
0
0
0
0
10
20
0
0
% A
% Cys:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
20
20
0
0
0
20
0
0
0
60
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
0
0
10
10
60
0
30
0
0
0
0
60
0
30
% K
% Leu:
0
0
0
0
0
10
0
0
0
60
0
30
0
50
0
% L
% Met:
0
0
50
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
60
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
60
10
70
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
60
0
10
0
0
% Q
% Arg:
0
0
0
0
20
10
10
0
0
20
0
0
10
20
0
% R
% Ser:
0
10
0
0
0
0
0
60
0
10
10
0
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
60
0
10
0
0
0
0
0
0
0
0
60
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
60
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _