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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf25 All Species: 22.73
Human Site: S64 Identified Species: 55.56
UniProt: Q8IW50 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IW50 NP_671735.1 185 20400 S64 R E L A R K G S L K N G S M G
Chimpanzee Pan troglodytes XP_001161024 185 20399 S64 R E M A R K G S L K N G S M G
Rhesus Macaque Macaca mulatta XP_001088997 270 28968 S149 R E L A R K G S L K N G S M G
Dog Lupus familis XP_531979 185 20381 S64 R E L A R K G S L K N G S M G
Cat Felis silvestris
Mouse Mus musculus Q9D772 157 17474 M42 G S L K N G S M G S P V N Q Q
Rat Rattus norvegicus NP_001103086 157 17476 M42 G S L K N S S M G S P V N Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511942 230 24741 R107 H T K L Q K H R D L A K A A L
Chicken Gallus gallus XP_001231783 185 20582 S64 R E L A R K G S L K N G N M G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DC60 186 20685 S65 R E L A R K G S V K N G T V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178400 193 22137 P65 Q R E A V R N P H H R P L N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 68.1 100 N.A. 83.7 83.7 N.A. 36.5 95.1 N.A. 87 N.A. N.A. N.A. N.A. 39.3
Protein Similarity: 100 100 68.1 100 N.A. 84.3 83.7 N.A. 50 96.7 N.A. 91.9 N.A. N.A. N.A. N.A. 55.4
P-Site Identity: 100 93.3 100 100 N.A. 6.6 6.6 N.A. 6.6 93.3 N.A. 80 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 13.3 13.3 N.A. 20 100 N.A. 100 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 70 0 0 0 0 0 0 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 60 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 0 0 0 10 60 0 20 0 0 60 0 0 60 % G
% His: 10 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 20 0 70 0 0 0 60 0 10 0 0 0 % K
% Leu: 0 0 70 10 0 0 0 0 50 10 0 0 10 0 10 % L
% Met: 0 0 10 0 0 0 0 20 0 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 20 0 10 0 0 0 60 0 30 10 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 20 10 0 0 0 % P
% Gln: 10 0 0 0 10 0 0 0 0 0 0 0 0 20 20 % Q
% Arg: 60 10 0 0 60 10 0 10 0 0 10 0 0 0 0 % R
% Ser: 0 20 0 0 0 10 20 60 0 20 0 0 40 0 10 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 10 0 0 0 10 0 0 20 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _