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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf25
All Species:
22.73
Human Site:
S72
Identified Species:
55.56
UniProt:
Q8IW50
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW50
NP_671735.1
185
20400
S72
L
K
N
G
S
M
G
S
P
V
N
Q
Q
P
K
Chimpanzee
Pan troglodytes
XP_001161024
185
20399
S72
L
K
N
G
S
M
G
S
P
V
N
Q
Q
P
K
Rhesus Macaque
Macaca mulatta
XP_001088997
270
28968
S157
L
K
N
G
S
M
G
S
P
V
N
Q
Q
P
K
Dog
Lupus familis
XP_531979
185
20381
S72
L
K
N
G
S
M
G
S
P
V
N
Q
Q
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D772
157
17474
P50
G
S
P
V
N
Q
Q
P
K
K
N
N
V
M
A
Rat
Rattus norvegicus
NP_001103086
157
17476
P50
G
S
P
V
N
Q
Q
P
K
K
N
N
V
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511942
230
24741
R115
D
L
A
K
A
A
L
R
R
K
G
I
L
G
G
Chicken
Gallus gallus
XP_001231783
185
20582
S72
L
K
N
G
N
M
G
S
P
V
N
Q
Q
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DC60
186
20685
S73
V
K
N
G
T
V
G
S
P
V
N
Q
Q
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178400
193
22137
P73
H
H
R
P
L
N
S
P
S
P
V
E
S
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
68.1
100
N.A.
83.7
83.7
N.A.
36.5
95.1
N.A.
87
N.A.
N.A.
N.A.
N.A.
39.3
Protein Similarity:
100
100
68.1
100
N.A.
84.3
83.7
N.A.
50
96.7
N.A.
91.9
N.A.
N.A.
N.A.
N.A.
55.4
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
0
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
6.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
60
0
0
60
0
0
0
10
0
0
10
10
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
60
0
10
0
0
0
0
20
30
0
0
0
0
60
% K
% Leu:
50
10
0
0
10
0
10
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
50
0
0
0
0
0
0
0
20
0
% M
% Asn:
0
0
60
0
30
10
0
0
0
0
80
20
0
0
0
% N
% Pro:
0
0
20
10
0
0
0
30
60
10
0
0
0
60
10
% P
% Gln:
0
0
0
0
0
20
20
0
0
0
0
60
60
10
0
% Q
% Arg:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
40
0
10
60
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
20
0
10
0
0
0
60
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _