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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINA12
All Species:
17.88
Human Site:
T291
Identified Species:
49.17
UniProt:
Q8IW75
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW75
NP_776249.1
414
47175
T291
E
K
G
L
Q
V
D
T
F
S
R
W
K
T
L
Chimpanzee
Pan troglodytes
XP_523013
414
47176
T291
E
K
G
L
Q
V
D
T
F
S
R
W
K
T
L
Rhesus Macaque
Macaca mulatta
XP_001099453
414
47043
T291
E
K
G
L
Q
V
D
T
F
S
R
W
K
T
L
Dog
Lupus familis
XP_855210
414
46891
T291
E
E
A
L
K
A
D
T
F
D
R
W
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMF5
413
47616
I291
E
Q
G
L
Q
A
D
I
F
A
K
W
K
S
L
Rat
Rattus norvegicus
Q8R4Z1
411
47509
I291
E
Q
G
L
Q
A
D
I
F
A
K
W
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511350
537
59894
T414
E
A
E
L
Q
K
D
T
V
A
R
W
K
K
L
Chicken
Gallus gallus
XP_421345
432
49179
T304
E
D
A
L
L
K
R
T
V
S
K
W
E
K
L
Frog
Xenopus laevis
NP_001087296
431
48852
V309
E
E
A
L
E
T
P
V
V
K
S
W
R
K
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
91.3
67.1
N.A.
61.3
62.3
N.A.
39.2
39.5
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
95.8
83
N.A.
81.4
82.6
N.A.
58.8
61.1
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
60
60
N.A.
60
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
66.6
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
34
0
0
34
0
0
0
34
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
78
0
0
12
0
0
0
0
0
% D
% Glu:
100
23
12
0
12
0
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% F
% Gly:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
12
% I
% Lys:
0
34
0
0
12
23
0
0
0
12
34
0
78
45
0
% K
% Leu:
0
0
0
100
12
0
0
0
0
0
0
0
0
0
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
23
0
0
67
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
56
0
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
45
12
0
0
23
0
% S
% Thr:
0
0
0
0
0
12
0
67
0
0
0
0
0
34
0
% T
% Val:
0
0
0
0
0
34
0
12
34
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _