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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR75 All Species: 26.67
Human Site: S763 Identified Species: 45.13
UniProt: Q8IWA0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWA0 NP_115544.1 830 94499 S763 L L S K E T K S A K E I P E D
Chimpanzee Pan troglodytes XP_001164827 830 94495 S763 L L S K E T K S A K E I P E D
Rhesus Macaque Macaca mulatta XP_001106363 830 94421 S763 L L S K E T K S A K E I P E D
Dog Lupus familis XP_545565 829 94501 S763 L L S K E T K S G E E I P E D
Cat Felis silvestris
Mouse Mus musculus NP_082875 830 94018 S762 L L S K E T K S A E E V P D D
Rat Rattus norvegicus NP_001041354 649 74096 A583 L S K E T K S A E E I S D D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520401 496 54144 E431 K A D D V E M E N E E E E E E
Chicken Gallus gallus XP_001233408 833 93957 S765 L V S K E N K S T E E T P D E
Frog Xenopus laevis Q6DFC6 832 94031 S766 L I S K K S Q S T E E S K E D
Zebra Danio Brachydanio rerio Q7ZVR1 832 93918 R760 L I S N T G V R E E M D S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610086 1071 119989 S983 L I P A D S T S R H S S S A A
Honey Bee Apis mellifera XP_623200 807 90558 D742 Q S I D D K V D K D N I T Q K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798367 969 106463 E892 S N T G A D S E S E D S D D E
Poplar Tree Populus trichocarpa XP_002329663 812 88693 K746 G D L E E A G K F G Y A S I Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 90.7 N.A. 84.9 64.2 N.A. 31.5 61.8 60.8 53.8 N.A. 24.2 26.1 N.A. 29.4
Protein Similarity: 100 100 99.4 95.3 N.A. 92.4 70.4 N.A. 40.9 77.1 76.6 70.6 N.A. 40 45.2 N.A. 46.7
P-Site Identity: 100 100 100 86.6 N.A. 80 6.6 N.A. 13.3 53.3 46.6 13.3 N.A. 13.3 6.6 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 33.3 N.A. 26.6 80 80 33.3 N.A. 33.3 20 N.A. 40
Percent
Protein Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 44.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 8 0 8 29 0 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 15 15 8 0 8 0 8 8 8 15 29 43 % D
% Glu: 0 0 0 15 50 8 0 15 15 58 58 8 8 43 29 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 8 8 0 8 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 22 8 0 0 0 0 0 0 0 8 36 0 8 0 % I
% Lys: 8 0 8 50 8 15 43 8 8 22 0 0 8 0 8 % K
% Leu: 72 36 8 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 8 0 8 0 0 8 0 8 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 0 43 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % R
% Ser: 8 15 58 0 0 15 15 58 8 0 8 29 22 8 0 % S
% Thr: 0 0 8 0 15 36 8 0 15 0 0 8 8 0 0 % T
% Val: 0 8 0 0 8 0 15 0 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _