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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR75
All Species:
18.79
Human Site:
S782
Identified Species:
31.79
UniProt:
Q8IWA0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWA0
NP_115544.1
830
94499
S782
E
E
K
E
S
E
D
S
D
E
E
N
D
F
T
Chimpanzee
Pan troglodytes
XP_001164827
830
94495
S782
E
E
K
E
S
E
D
S
D
E
E
N
D
F
T
Rhesus Macaque
Macaca mulatta
XP_001106363
830
94421
S782
E
E
K
E
S
E
D
S
D
E
E
N
D
F
I
Dog
Lupus familis
XP_545565
829
94501
S781
E
G
K
E
S
N
D
S
D
E
E
K
D
F
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_082875
830
94018
D782
N
K
E
S
D
D
S
D
E
E
Y
D
L
T
E
Rat
Rattus norvegicus
NP_001041354
649
74096
S601
G
N
E
E
S
D
D
S
D
E
E
Y
D
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520401
496
54144
D449
E
E
E
K
A
A
E
D
S
N
E
E
N
H
Q
Chicken
Gallus gallus
XP_001233408
833
93957
D785
E
E
A
E
D
D
S
D
E
E
N
S
V
T
E
Frog
Xenopus laevis
Q6DFC6
832
94031
D784
K
S
E
H
S
E
A
D
S
S
D
E
T
E
E
Zebra Danio
Brachydanio rerio
Q7ZVR1
832
93918
S779
S
E
K
E
E
E
E
S
E
E
E
M
E
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610086
1071
119989
E1014
G
H
Q
D
S
D
G
E
H
E
D
E
E
L
G
Honey Bee
Apis mellifera
XP_623200
807
90558
E760
E
D
S
A
E
E
S
E
G
E
L
S
R
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798367
969
106463
D914
L
D
S
D
M
E
T
D
D
V
H
V
A
P
P
Poplar Tree
Populus trichocarpa
XP_002329663
812
88693
K764
P
Q
F
D
P
K
R
K
Q
A
S
W
V
P
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
90.7
N.A.
84.9
64.2
N.A.
31.5
61.8
60.8
53.8
N.A.
24.2
26.1
N.A.
29.4
Protein Similarity:
100
100
99.4
95.3
N.A.
92.4
70.4
N.A.
40.9
77.1
76.6
70.6
N.A.
40
45.2
N.A.
46.7
P-Site Identity:
100
100
93.3
80
N.A.
6.6
60
N.A.
20
26.6
13.3
46.6
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
40
73.3
N.A.
53.3
46.6
33.3
66.6
N.A.
46.6
33.3
N.A.
26.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
8
0
0
8
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
15
0
22
15
29
36
36
43
0
15
8
36
0
0
% D
% Glu:
50
43
29
50
15
50
15
15
22
72
50
22
15
8
22
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
29
0
% F
% Gly:
15
8
0
0
0
0
8
0
8
0
0
0
0
0
8
% G
% His:
0
8
0
8
0
0
0
0
8
0
8
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
36
8
0
8
0
8
0
0
0
8
0
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
8
0
8
15
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
8
0
0
0
8
0
0
0
8
8
22
8
0
0
% N
% Pro:
8
0
0
0
8
0
0
0
0
0
0
0
0
15
8
% P
% Gln:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
8
8
15
8
50
0
22
43
15
8
8
15
0
8
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
15
29
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _