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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR75
All Species:
13.33
Human Site:
T789
Identified Species:
22.56
UniProt:
Q8IWA0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWA0
NP_115544.1
830
94499
T789
S
D
E
E
N
D
F
T
E
K
V
Q
D
T
S
Chimpanzee
Pan troglodytes
XP_001164827
830
94495
T789
S
D
E
E
N
D
F
T
K
K
V
Q
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001106363
830
94421
I789
S
D
E
E
N
D
F
I
E
K
V
Q
D
T
N
Dog
Lupus familis
XP_545565
829
94501
T788
S
D
E
E
K
D
F
T
E
K
I
E
D
T
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_082875
830
94018
E789
D
E
E
Y
D
L
T
E
K
D
K
E
T
N
N
Rat
Rattus norvegicus
NP_001041354
649
74096
T608
S
D
E
E
Y
D
L
T
E
K
A
K
E
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520401
496
54144
Q456
D
S
N
E
E
N
H
Q
T
K
V
D
Q
D
D
Chicken
Gallus gallus
XP_001233408
833
93957
E792
D
E
E
N
S
V
T
E
M
K
Q
E
D
K
M
Frog
Xenopus laevis
Q6DFC6
832
94031
E791
D
S
S
D
E
T
E
E
M
E
S
Q
K
R
F
Zebra Danio
Brachydanio rerio
Q7ZVR1
832
93918
C786
S
E
E
E
M
E
A
C
D
G
Q
Q
E
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610086
1071
119989
G1021
E
H
E
D
E
E
L
G
E
E
A
R
N
T
L
Honey Bee
Apis mellifera
XP_623200
807
90558
K767
E
G
E
L
S
R
S
K
K
Q
E
S
P
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798367
969
106463
P921
D
D
V
H
V
A
P
P
M
A
T
G
A
S
T
Poplar Tree
Populus trichocarpa
XP_002329663
812
88693
S771
K
Q
A
S
W
V
P
S
A
S
L
E
R
P
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
90.7
N.A.
84.9
64.2
N.A.
31.5
61.8
60.8
53.8
N.A.
24.2
26.1
N.A.
29.4
Protein Similarity:
100
100
99.4
95.3
N.A.
92.4
70.4
N.A.
40.9
77.1
76.6
70.6
N.A.
40
45.2
N.A.
46.7
P-Site Identity:
100
93.3
86.6
73.3
N.A.
6.6
66.6
N.A.
20
20
6.6
26.6
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
40
80
N.A.
26.6
40
20
53.3
N.A.
53.3
26.6
N.A.
20
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
8
0
8
8
15
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
36
43
0
15
8
36
0
0
8
8
0
8
36
8
8
% D
% Glu:
15
22
72
50
22
15
8
22
36
15
8
29
15
0
0
% E
% Phe:
0
0
0
0
0
0
29
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
8
0
8
0
8
0
0
0
% G
% His:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
8
22
50
8
8
8
8
0
% K
% Leu:
0
0
0
8
0
8
15
0
0
0
8
0
0
8
8
% L
% Met:
0
0
0
0
8
0
0
0
22
0
0
0
0
0
8
% M
% Asn:
0
0
8
8
22
8
0
0
0
0
0
0
8
8
22
% N
% Pro:
0
0
0
0
0
0
15
8
0
0
0
0
8
8
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
8
15
36
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
8
8
15
8
% R
% Ser:
43
15
8
8
15
0
8
8
0
8
8
8
0
8
22
% S
% Thr:
0
0
0
0
0
8
15
29
8
0
8
0
8
43
8
% T
% Val:
0
0
8
0
8
15
0
0
0
0
29
0
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _