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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR75
All Species:
24.85
Human Site:
Y657
Identified Species:
42.05
UniProt:
Q8IWA0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWA0
NP_115544.1
830
94499
Y657
W
L
N
R
S
Q
F
Y
F
L
T
K
S
Q
S
Chimpanzee
Pan troglodytes
XP_001164827
830
94495
Y657
W
L
N
R
S
Q
F
Y
F
L
T
K
S
Q
S
Rhesus Macaque
Macaca mulatta
XP_001106363
830
94421
Y657
W
L
N
R
S
Q
F
Y
F
L
T
K
S
Q
S
Dog
Lupus familis
XP_545565
829
94501
F657
W
L
N
R
S
Q
F
F
F
L
T
K
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_082875
830
94018
Y656
W
L
N
R
S
Q
F
Y
F
L
T
K
S
Q
S
Rat
Rattus norvegicus
NP_001041354
649
74096
T479
R
S
Q
F
Y
F
L
T
E
S
Q
C
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520401
496
54144
S327
Q
D
L
M
T
F
S
S
N
S
P
E
E
K
L
Chicken
Gallus gallus
XP_001233408
833
93957
F661
W
L
R
R
S
Q
L
F
F
L
T
D
T
Q
E
Frog
Xenopus laevis
Q6DFC6
832
94031
Y660
W
L
N
K
S
Q
L
Y
F
L
T
E
K
Q
D
Zebra Danio
Brachydanio rerio
Q7ZVR1
832
93918
Y655
W
L
N
R
S
Q
L
Y
F
L
T
H
N
M
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610086
1071
119989
D814
S
V
R
Q
L
A
F
D
P
L
T
N
L
M
A
Honey Bee
Apis mellifera
XP_623200
807
90558
D638
R
S
Q
L
F
F
L
D
S
N
Q
E
L
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798367
969
106463
Y783
W
Q
Q
D
S
E
L
Y
F
M
T
K
S
Q
E
Poplar Tree
Populus trichocarpa
XP_002329663
812
88693
L642
F
F
A
A
L
A
L
L
P
E
S
S
K
W
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
90.7
N.A.
84.9
64.2
N.A.
31.5
61.8
60.8
53.8
N.A.
24.2
26.1
N.A.
29.4
Protein Similarity:
100
100
99.4
95.3
N.A.
92.4
70.4
N.A.
40.9
77.1
76.6
70.6
N.A.
40
45.2
N.A.
46.7
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
0
60
66.6
66.6
N.A.
20
0
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
20
73.3
80
73.3
N.A.
40
13.3
N.A.
66.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
15
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
15
0
0
0
8
0
0
15
% D
% Glu:
0
0
0
0
0
8
0
0
8
8
0
22
8
0
15
% E
% Phe:
8
8
0
8
8
22
43
15
65
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
43
15
8
0
% K
% Leu:
0
58
8
8
15
0
50
8
0
65
0
0
22
15
8
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
15
0
% M
% Asn:
0
0
50
0
0
0
0
0
8
8
0
8
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
8
0
0
0
0
% P
% Gln:
8
8
22
8
0
58
0
0
0
0
15
0
0
58
0
% Q
% Arg:
15
0
15
50
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
15
0
0
65
0
8
8
8
15
8
8
43
0
36
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
72
0
8
0
15
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
65
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
8
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _