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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFN1
All Species:
42.73
Human Site:
T185
Identified Species:
94
UniProt:
Q8IWA4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IWA4
NP_284941.2
741
84100
T185
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Chimpanzee
Pan troglodytes
XP_001167765
769
87046
T213
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Rhesus Macaque
Macaca mulatta
XP_001108853
741
84052
T185
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Dog
Lupus familis
XP_545210
742
84100
T185
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Cat
Felis silvestris
Mouse
Mus musculus
Q811U4
741
83721
T185
D
S
P
G
T
D
V
T
T
E
L
D
I
W
I
Rat
Rattus norvegicus
Q8R4Z9
741
83829
T185
D
S
P
G
T
D
V
T
T
E
L
D
I
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505565
839
94273
T207
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085532
738
83413
T186
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Zebra Danio
Brachydanio rerio
NP_956941
740
84251
T186
D
S
P
G
T
D
V
T
T
E
L
D
S
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7YU24
810
91354
S246
D
S
P
G
V
D
V
S
A
N
L
D
D
W
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23424
774
87443
S218
D
S
P
G
V
D
L
S
P
E
F
D
S
W
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
97.5
91.6
N.A.
90.2
90.2
N.A.
74.1
N.A.
68.4
69.3
N.A.
43.5
N.A.
32.5
N.A.
Protein Similarity:
100
96
99.1
96.2
N.A.
95.8
95.4
N.A.
81.5
N.A.
83.6
83.2
N.A.
61.2
N.A.
55.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
100
100
N.A.
66.6
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
100
100
N.A.
73.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
100
0
0
0
0
0
100
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
100
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
91
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
100
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
100
0
0
0
0
0
19
0
0
0
0
73
0
0
% S
% Thr:
0
0
0
0
82
0
0
82
82
0
0
0
0
0
0
% T
% Val:
0
0
0
0
19
0
91
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _