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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFN1 All Species: 24.24
Human Site: T562 Identified Species: 53.33
UniProt: Q8IWA4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWA4 NP_284941.2 741 84100 T562 L P R S L A S T P T A P T T P
Chimpanzee Pan troglodytes XP_001167765 769 87046 T590 L P R S L A S T P T A P T T P
Rhesus Macaque Macaca mulatta XP_001108853 741 84052 T562 L P R S L A S T P S A P T T P
Dog Lupus familis XP_545210 742 84100 T562 L P R S L A S T P T A P T N P
Cat Felis silvestris
Mouse Mus musculus Q811U4 741 83721 T562 V P R S L A S T P T A P S N P
Rat Rattus norvegicus Q8R4Z9 741 83829 T562 V P R S L A S T P T A P S N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505565 839 94273 P585 P R S L A S T P T A A P T N P
Chicken Gallus gallus
Frog Xenopus laevis NP_001085532 738 83413 P562 I P Q P V T T P S A T V N P I
Zebra Danio Brachydanio rerio NP_956941 740 84251 S564 T A P A V V Q S Q N S R A L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7YU24 810 91354 T635 T T T P V E A T P V C L L P A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23424 774 87443 E594 L S L K Q Q S E K N S V R D A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 97.5 91.6 N.A. 90.2 90.2 N.A. 74.1 N.A. 68.4 69.3 N.A. 43.5 N.A. 32.5 N.A.
Protein Similarity: 100 96 99.1 96.2 N.A. 95.8 95.4 N.A. 81.5 N.A. 83.6 83.2 N.A. 61.2 N.A. 55.8 N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 80 80 N.A. 26.6 N.A. 6.6 0 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 40 N.A. 33.3 26.6 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 55 10 0 0 19 64 0 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 46 0 10 10 55 0 0 0 0 0 0 10 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 19 0 0 10 37 0 % N
% Pro: 10 64 10 19 0 0 0 19 64 0 0 64 0 19 64 % P
% Gln: 0 0 10 0 10 10 10 0 10 0 0 0 0 0 0 % Q
% Arg: 0 10 55 0 0 0 0 0 0 0 0 10 10 0 0 % R
% Ser: 0 10 10 55 0 10 64 10 10 10 19 0 19 0 0 % S
% Thr: 19 10 10 0 0 10 19 64 10 46 10 0 46 28 0 % T
% Val: 19 0 0 0 28 10 0 0 0 10 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _