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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC44A2 All Species: 23.64
Human Site: T631 Identified Species: 52
UniProt: Q8IWA5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IWA5 NP_065161.3 706 80152 T631 R I R I V Q D T A P P L N Y Y
Chimpanzee Pan troglodytes XP_001165902 706 80119 T631 R I R I V Q D T A P P L N Y Y
Rhesus Macaque Macaca mulatta XP_001100446 717 81561 G642 R L P V I A Q G P A S L N Y Y
Dog Lupus familis XP_868166 704 79909 T629 R I R I V Q D T A P P L N Y Y
Cat Felis silvestris
Mouse Mus musculus Q8BY89 704 79905 T629 R I R I V Q D T A P P L N Y Y
Rat Rattus norvegicus B4F795 705 79878 T630 R I R I V Q D T A P P L N Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426673 715 81291 E638 R I P V F A Q E A P A L N Y Y
Frog Xenopus laevis Q6IP59 710 80675 T635 R I Q I V Q D T A P T L N Y Y
Zebra Danio Brachydanio rerio B0S5A7 700 79484 E609 Q I P V I Q E E V P S L N Y Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAP3 796 90611 S717 Y F L D N N P S I I R L N Y I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20026 771 87293 P695 R W V V E G V P K V D L Y Y Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 54.1 93.6 N.A. 90.5 91.9 N.A. N.A. 63.7 76 60.9 N.A. 32 N.A. 37.7 N.A.
Protein Similarity: 100 100 73.2 95.8 N.A. 95.4 96.5 N.A. N.A. 79.4 88.5 77 N.A. 49.8 N.A. 57 N.A.
P-Site Identity: 100 100 33.3 100 N.A. 100 100 N.A. N.A. 53.3 86.6 46.6 N.A. 20 N.A. 26.6 N.A.
P-Site Similarity: 100 100 53.3 100 N.A. 100 100 N.A. N.A. 60 93.3 73.3 N.A. 26.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 19 0 0 64 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 55 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 10 19 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 73 0 55 19 0 0 0 10 10 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 10 10 0 0 0 0 0 0 0 0 100 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 91 0 0 % N
% Pro: 0 0 28 0 0 0 10 10 10 73 46 0 0 0 0 % P
% Gln: 10 0 10 0 0 64 19 0 0 0 0 0 0 0 0 % Q
% Arg: 82 0 46 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 19 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 55 0 0 10 0 0 0 0 % T
% Val: 0 0 10 37 55 0 10 0 10 10 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 10 100 91 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _